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Reactome Pathway Database

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MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH

Stable Identifier
R-HSA-5603060
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
MAEL:MeR-PIWIL4:2'-O-methy-piRNA:TDRD9:TDRKH
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
    • Gene Silencing by RNA (Homo sapiens)
      • PIWI-interacting RNA (piRNA) biogenesis (Homo sapiens)
        • HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH (Homo sapiens)
          • MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
        • MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events (Homo sapiens)
          • MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
Participants
components
  • MAEL [cytosol] (Homo sapiens)
  • MeR-PIWIL4:2'-O-methy-piRNA [cytosol] (Homo sapiens)
  • TDRD9 [cytosol] (Homo sapiens)
  • TDRKH [cytosol] (Homo sapiens)
Participant Of
input
  • MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events
output
  • HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH
Inferred From
MeR-Piwil4:2'-O-methyl-piRNA:Tdrd9:Mael:Tdrkh [cytosol] (Mus musculus)

 

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