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MAEL [cytosol]
Stable Identifier
R-HSA-5603058
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Protein maelstrom homolog, MAEL_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
PIWI-interacting RNA (piRNA) biogenesis (Homo sapiens)
Complexed PIWIL4 binds cleaved transposon RNA (Homo sapiens)
MeR-PIWIL4:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
HENMT1 methylates 2' hydroxyl at 3' end of piRNA in MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
Unknown nuclease cleaves cleaved transposon RNA bound in MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MAEL [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96JY0 MAEL
Gene Names
MAEL
Chain
chain:1-434
Reference Genes
BioGPS Gene:84944 MAEL
COSMIC (genes):MAEL MAEL
CTD Gene:84944 MAEL
dbSNP Gene:84944 MAEL
ENSEMBL:ENSG00000143194 MAEL
HGNC:25929 MAEL
Monarch:84944 MAEL
NCBI Gene:84944 MAEL
OMIM:611368 MAEL
UCSC:Q96JY0 MAEL
Reference Transcript
RefSeq:NM_032858.2 MAEL
RefSeq:NM_001286377.1 MAEL
RefSeq:NM_001286378.1 MAEL
Other Identifiers
11736955_a_at
16673323
16673341
229475_PM_at
229475_at
2365598
2365602
2365603
2365604
2365605
2365607
2365608
2365609
2365610
2365612
2365613
2365614
2365615
2365616
2365617
2365618
2365620
2365621
2365623
2365624
2365625
2365626
2365627
60472_at
7907032
7907049
84944
A_14_P121669
A_23_P114934
GE86948
GO:0000122
GO:0000785
GO:0000902
GO:0001673
GO:0001741
GO:0003677
GO:0005634
GO:0005694
GO:0005737
GO:0006325
GO:0006355
GO:0006915
GO:0006974
GO:0007129
GO:0007140
GO:0007283
GO:0008630
GO:0009566
GO:0010467
GO:0010629
GO:0012501
GO:0022414
GO:0030154
GO:0030849
GO:0031047
GO:0033391
GO:0034587
GO:0035234
GO:0043066
GO:0043186
GO:0043226
GO:0043565
GO:0045892
GO:0046620
GO:0048471
GO:0051093
GO:0051321
GO:0060964
GO:0071514
GO:0071547
GO:0140013
GO:0141196
GO:2000242
HMNXSV003027310
Hs.180191.0.S1_3p_at
ILMN_2211479
ILMN_2211483
PH_hs_0010666
TC01001453.hg
TC01001454.hg
Participates
as a component of
MeR-PIWIL4:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:cleaved transposon RNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH [cytosol] (Homo sapiens)
Other forms of this molecule
MAEL [nucleoplasm]
Cross References
ENSEMBL
ENSP00000356846
,
ENSP00000356844
,
ENST00000367872
,
ENST00000367870
OpenTargets
ENSG00000143194
HPA
ENSG00000143194-MAEL
PRO
Q96JY0
Pharos - Targets
Q96JY0
PDB
2CTO
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