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MRPS21 [mitochondrial inner membrane]
Stable Identifier
R-HSA-5368261
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
28S ribosomal protein S21, mitochondrial, RT21_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
Mitochondrial translation (Homo sapiens)
Mitochondrial translation elongation (Homo sapiens)
55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
Peptide transfer from P-site to A-site (peptide bond formation) (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA:aminoacyl-tRNA:TUFM:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation initiation (Homo sapiens)
28S subunit:MTIF3 binds MTIF2:GTP, mRNA, and formylMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
39S subunit binds 28S subunit:mRNA:fMet-tRNA (Homo sapiens)
28S ribosomal subunit:MTIF3:MTIF2:GTP:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:fMet-tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
MTIF3 binds 28S ribosomal subunit (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit:MTIF3 [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
Mitochondrial translation termination (Homo sapiens)
55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)
55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Homo sapiens)
55S ribosome [mitochondrial inner membrane] (Homo sapiens)
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
MRPS21 [mitochondrial inner membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P82921 MRPS21
Gene Names
MRPS21, RPMS21, MDS016
Chain
chain:1-87
Reference Genes
BioGPS Gene:54460 MRPS21
COSMIC (genes):MRPS21 MRPS21
CTD Gene:54460 MRPS21
dbSNP Gene:54460 MRPS21
ENSEMBL:ENSG00000266472 MRPS21
ENSEMBL_homo_sapiens_GENE:ENSG00000266472.6 MRPS21
HGNC:14046 MRPS21
KEGG Gene (Homo sapiens):54460 MRPS21
Monarch:54460 MRPS21
NCBI Gene:54460 MRPS21
OMIM:611984 MRPS21
UCSC:P82921 MRPS21
Reference Transcript
RefSeq:NM_031901.5 MRPS21
RefSeq:NM_018997.3 MRPS21
Other Identifiers
11716312_at
11716313_x_at
11721298_a_at
11721299_x_at
16670492
222997_PM_s_at
222997_s_at
2358154
2358155
2358156
2358157
2358158
2358165
2358166
2358167
2358168
2358169
2358170
2416697
54460
7905163
A_14_P132684
A_23_P86182
A_24_P139816
GE542030
GE59440
GO:0003723
GO:0003735
GO:0005198
GO:0005739
GO:0005743
GO:0005763
GO:0005840
GO:0006412
GO:0032543
GO:0043226
GO:0140053
GO:1990904
HMNXSV003011449
ILMN_1655765
ILMN_1660292
PH_hs_0019214
PH_hs_0035906
TC01001184.hg
U79258_at
g13528740_3p_s_at
Participates
as a component of
28S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)
Inferred To
MRPS21 [mitochondrial inner membrane]
(Bos taurus)
MRPS21 [mitochondrial inner membrane]
(Canis familiaris)
MRPS21 [mitochondrial inner membrane]
(Gallus gallus)
MRPS21 [mitochondrial inner membrane]
(Sus scrofa)
mRpS21 [mitochondrial inner membrane]
(Drosophila melanogaster)
mrps21 [mitochondrial inner membrane]
(Danio rerio)
Mrps21 [mitochondrial inner membrane]
(Mus musculus)
Mrps21 [mitochondrial inner membrane]
(Rattus norvegicus)
mrps-21 [mitochondrial inner membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_114107.1
,
NP_061870.1
OpenTargets
ENSG00000266472
GeneCards
P82921
HPA
ENSG00000266472-MRPS21
Ensembl
ENST00000581066
,
ENSP00000461930
,
ENSP00000480129
,
ENSG00000266472
,
ENST00000614145
PRO
P82921
Pharos - Targets
P82921
PDB
8CST
,
6ZSG
,
7PO3
,
8CSU
,
7PO1
,
7A5I
,
8CSQ
,
6ZSC
,
8CSP
,
6ZSB
,
6NU3
,
7PNY
,
7P2E
,
7PO0
,
6ZSE
,
8CSS
,
6RW5
,
6RW4
,
7PO2
,
6ZSD
,
3J9M
,
7PNZ
,
7A5K
,
8CSR
,
8OIS
,
6ZS9
,
7PNX
,
6ZSA
,
7A5G
,
6VMI
,
7OG4
,
6NU2
,
7A5F
,
6VLZ
,
6ZM5
,
8OIR
,
7L08
,
6ZM6
,
8ANY
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