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SECISBP2 [cytosol]
Stable Identifier
R-HSA-5357715
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Selenocysteine insertion sequence-binding protein 2, SEBP2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Selenocysteine synthesis (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] (Homo sapiens)
SECISBP2 [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
SECISBP2 [cytosol] (Homo sapiens)
Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
SECISBP2 [cytosol] (Homo sapiens)
SECISBP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96T21 SECISBP2
Gene Names
SECISBP2, SBP2
Chain
chain:1-854
Reference Genes
BioGPS Gene:79048 SECISBP2
COSMIC (genes):SECISBP2 SECISBP2
CTD Gene:79048 SECISBP2
dbSNP Gene:79048 SECISBP2
ENSEMBL:ENSG00000187742 SECISBP2
ENSEMBL_homo_sapiens_GENE:ENSG00000187742.15 SECISBP2
HGNC:30972 SECISBP2
KEGG Gene (Homo sapiens):79048 SECISBP2
Monarch:79048 SECISBP2
NCBI Gene:79048 SECISBP2
OMIM:607693 SECISBP2
UCSC:Q96T21 SECISBP2
Reference Transcript
RefSeq:NM_001282689.1 SECISBP2
RefSeq:NM_001282688.1 SECISBP2
RefSeq:XM_011519000.2 SECISBP2
RefSeq:XM_006717282.2 SECISBP2
RefSeq:NM_024077.4 SECISBP2
Other Identifiers
11717600_a_at
11717601_s_at
11717602_a_at
11717603_a_at
11745990_x_at
11749102_a_at
17086640
218265_PM_at
218265_at
224250_PM_s_at
224250_s_at
3178613
3178614
3178615
3178619
3178620
3178621
3178622
3178623
3178624
3178625
3178626
3178629
3178633
3178634
3178635
3178637
3178639
3178640
4050234
4050235
4050236
4050237
4050238
4050241
4050242
4050246
4050249
4050250
4050253
47978_at
51608_at
52182_at
73439_at
79048
80656_s_at
8156295
A_23_P84872
A_24_P119482
A_33_P3393843
GE86705
GO:0001514
GO:0003677
GO:0003723
GO:0003730
GO:0005515
GO:0005634
GO:0005654
GO:0005739
GO:0006412
GO:0016071
GO:0021756
GO:0021884
GO:0030154
GO:0035368
GO:0043021
GO:0043226
GO:0048856
GO:1990904
GO:2000623
HMNXSV003002535
HMNXSV003007247
ILMN_1736481
PH_hs_0014939
PH_hs_0040620
TC09000417.hg
g12654698_3p_a_at
g13129065_3p_at
Participates
as a component of
80S:Met-tRNAi:mRNA:SECISBP2:Sec [cytosol] (Homo sapiens)
80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP [cytosol] (Homo sapiens)
as an input of
Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)
Cross References
RefSeq
NP_076982.3
,
XP_011517302.1
,
XP_006717345.1
,
NP_001269618.1
,
NP_001269617.1
OpenTargets
ENSG00000187742
HPA
ENSG00000187742-SECISBP2
GeneCards
Q96T21
Ensembl
ENSP00000364959
,
ENST00000339901
,
ENSG00000187742
,
ENST00000375807
,
ENSP00000436650
,
ENSP00000364965
,
ENST00000534113
PRO
Q96T21
Pharos - Targets
Q96T21
Orphanet
18164
PDB
7ZJX
,
7ZJW
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92567-2 FAM168A
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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