p-AXL binds PI3K

Stable Identifier
R-HSA-5357479
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Axl with its two phopshorylated YxxM motifs associates with the p85 subunit of PI3K and mediates VEGFA mediated activation of PI3K/AKT pathway (Ruan & Kazlauskas, 2012).

Literature References
PubMed ID Title Journal Year
22327215 Axl is essential for VEGF-A-dependent activation of PI3K/Akt

Ruan, GX, Kazlauskas, A

EMBO J. 2012
Participants
Participant Of
Orthologous Events
Authored
Reviewed