PAK1-3 dimer disassociates

Stable Identifier
R-HSA-5357445
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
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Binding of Rac1 increases p21 activated kinases 1-3 (PAK1-3) kinase activity and breaks the PAK dimer into monomers.

Literature References
PubMed ID Title Journal Year
11804587 Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

Parrini, MC, Lei, M, Harrison, SC, Mayer, BJ

Mol Cell 2002
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created