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TET3 [nucleoplasm]
Stable Identifier
R-HSA-5220918
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Methylcytosine dioxygenase TET3 ecNumber1.14.11.n2/ecNumber, TET3_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Chromatin modifications during the maternal to zygotic transition (MZT) (Homo sapiens)
TET3 binds chromatin with H3K17me2a and 5-mC:METTL23:STGP4 (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET3:STGP4:METTL23:Chromatin with H3.3 dimethylarginine-17, H2A.x, and 5-mC [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET3:STGP4:METTL23:Chromatin with H3.3 dimethylarginine-17, H2A.x, and 5-mC [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET3:STGP4:METTL23:Chromatin with H3.3 dimethylarginine-4 and 5-hmC [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
TET1,2,3 and TDG demethylate DNA (Homo sapiens)
TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine (Homo sapiens)
TET1,2,3 [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine (Homo sapiens)
TET1,2,3 [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine (Homo sapiens)
TET1,2,3 [nucleoplasm] (Homo sapiens)
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
TET3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43151 TET3
Gene Names
TET3, KIAA0401
Chain
chain:1-1795
Reference Genes
BioGPS Gene:200424 TET3
COSMIC (genes):TET3 TET3
CTD Gene:200424 TET3
dbSNP Gene:200424 TET3
ENSEMBL:ENSG00000187605 TET3
HGNC:28313 TET3
Monarch:200424 TET3
NCBI Gene:200424 TET3
OMIM:613555 TET3
UCSC:O43151 TET3
Reference Transcript
RefSeq:XM_005264187.3 TET3
RefSeq:NM_001287491.1 TET3
Other Identifiers
11729924_at
11729925_a_at
1554641_PM_a_at
1554641_a_at
16881629
16881631
16881634
200424
214754_PM_at
214754_at
235542_PM_at
235542_at
2489068
2489069
2489072
2489073
2489075
2489076
2489082
2489083
2489084
2489085
2489086
2489087
2489092
2489093
2489094
2489100
2489102
2489103
2489104
2489105
2489106
2489107
2489108
2489109
2489110
2489111
2489112
2489114
2489116
2489118
38559_at
61868_at
8042811
81423_at
A_32_P542874
A_33_P3235177
A_33_P3276237
A_33_P3331335
A_33_P3345001
GE507662
GE53162
GO:0000978
GO:0001939
GO:0001940
GO:0003677
GO:0003824
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0006211
GO:0006325
GO:0006355
GO:0006486
GO:0006493
GO:0008270
GO:0008327
GO:0010468
GO:0016491
GO:0043226
GO:0044029
GO:0044727
GO:0045944
GO:0046872
GO:0051213
GO:0070579
GO:0141166
HMNXSV003013275
HMNXSV003046899
Hs.118047.0.A1_3p_at
Hs.17803.0.A1_3p_at
Hs2.17803.1.A1_3p_s_at
ILMN_1759352
ILMN_1787155
PH_hs_0033497
PH_hs_0037009
TC02000450.hg
TC02000451.hg
TC02003332.hg
p9853
p9854
Participates
as a component of
TET3:Fe2+ [nucleoplasm] (Homo sapiens)
Cross References
ENSEMBL
ENSP00000386869
,
ENST00000409262
OpenTargets
ENSG00000187605
HPA
ENSG00000187605-TET3
PRO
O43151
Pharos - Targets
O43151
GlyGen
O43151
HMDB Protein
HMDBP11974
PDB
4Z3C
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O15294 OGT
2
OGT [nucleoplasm]
(R-HSA-3321845)
OGT [cytosol]
(R-HSA-9687814)
0.739
7
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