Reactome | OTUD7B [cytosol]

OTUD7B [cytosol]

Stable Identifier

R-HSA-5212662

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ZA20D1, OTU domain-containing protein 7B, Cezanne

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6GQQ9 OTUD7B

Gene Names

OTUD7B, ZA20D1

Chain

chain:1-843

Reference Genes

BioGPS Gene:56957 Q6GQQ92

COSMIC - genes:OTUD7B OTUD7B

CTD Gene:56957 Q6GQQ92

dbSNP Gene:56957 OTUD7B

ENSEMBL:ENSG00000264522 OTUD7B

HGNC:16683 Q6GQQ92

KEGG:hsa:56957 Q6GQQ92

Monarch:56957 Q6GQQ92

NCBI Gene:56957 Q6GQQ92

OMIM:611748 Q6GQQ92

UCSC:Q6GQQ9 Q6GQQ92

Reference Transcript

Participates

as a member of

OTUD7B,TNFAIP3,ZRANB1 [cytosol] (Homo sapiens)

as a candidate of

RIPK1 deubiquitinases [cytosol] (Homo sapiens)

Inferred To

otud7b [cytosol] (Xenopus tropicalis)

Otud7b [cytosol] (Rattus norvegicus)

OTUD7B [cytosol] (Bos taurus)

OTUD7B [cytosol] (Canis familiaris)

OTUD7B [cytosol] (Gallus gallus)

OTUD7B [cytosol] (Mus musculus)

OTUD7B [cytosol] (Sus scrofa)

Cross References

RefSeq

XP_054193739.1, XP_054193738.1, NP_064590.2, XP_047281673.1, XP_054193740.1, XP_047281677.1, XP_047281676.1

ENSEMBL

ENSP00000462729, ENST00000581312, ENSG00000264522

OpenTargets

ENSG00000264522

IntEnz

3.4.19.12

GeneCards

OTUD7B

HPA

ENSG00000264522-OTUD7B

PRO

Q6GQQ9

Pharos - Targets

Q6GQQ9

GlyGen

Q6GQQ9

PDB

5LRU, 5LRW, 5LRV

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BN8 OTULIN	1	OTULIN [cytosol] (R-HSA-5661503)	0.556	3
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [secretory granule lumen] (R-HSA-6803287)	0.556	3
UniProt:Q8NFZ5 TNIP2	1	TNIP2 [cytosol] (R-HSA-451661)	0.547	2
UniProt:Q99497 PARK7	7	PolyUb-Misfolded PARK7 [lysosomal lumen] (R-HSA-9659997) PolyUb-Misfolded PARK7 [cytosol] (R-HSA-9641128) Ub-Misfolded PARK7 [cytosol] (R-HSA-9641123) Misfolded PARK7 [cytosol] (R-HSA-9641100) PolyUb-Misfolded PARK7 [late endosome lumen] (R-HSA-9660005) PARK7 [nucleoplasm] (R-HSA-3900141) monoSUMO1-K130-PARK7 [nucleoplasm] (R-HSA-4085351)	0.524	3

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