WNT5A-dependent FZD4 uptake into clathrin-coated vesicles depends upon AP-2 and possibly ARBB2 (Chen et al, 2003; Yu et al, 2007). Evidence suggests that ARBB2 dissociates from the receptor-ligand complex before internalization (Chen et al, 2003).
Chen, W, ten Berge, D, Brown, J, Ahn, S, Hu, LA, Miller, WE, Caron, MG, Barak, LS, Nusse, R, Lefkowitz, RJ
Yu, A, Rual, JF, Tamai, K, Harada, Y, Vidal, M, He, X, Kirchhausen, T
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