Reactome | POU5F1:SOX2:NANOG:SOX2 gene [nucleoplasm]

Stable Identifier

R-HSA-480572

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

OCT4:SOX2:NANOG:SOX2 gene

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
16153702	Core transcriptional regulatory circuitry in human embryonic stem cells	Cell	2005
18212089	High-throughput biochemical analysis of in vivo location data reveals novel distinct classes of POU5F1(Oct4)/DNA complexes	Genome Res	2008
15860457	Transcriptional regulation of nanog by OCT4 and SOX2	J Biol Chem	2005
22215994	Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development	PLoS Comput. Biol.	2011
15988017	Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells	Mol Cell Biol	2005

Participants

components

Participant Of

output

This entity regulates

Positive Regulation