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KDM5C [nucleoplasm]
Stable Identifier
R-HSA-4754186
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Lysine-specific demethylase 5C ecNumber1.14.11.-/ecNumber, KDM5C_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HDMs demethylate histones (Homo sapiens)
KDM5A-D demethylate Me2K5-histone H3 (Homo sapiens)
KDM5A-D [nucleoplasm] (Homo sapiens)
KDM5C [nucleoplasm] (Homo sapiens)
KDM5A-D demethylate Me3K5-histone H3 (Homo sapiens)
KDM5A-D [nucleoplasm] (Homo sapiens)
KDM5C [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P41229 KDM5C
Gene Names
KDM5C, DXS1272E, JARID1C, SMCX, XE169
Chain
chain:1-1560
Reference Genes
BioGPS Gene:8242 KDM5C
COSMIC (genes):KDM5C KDM5C
CTD Gene:8242 KDM5C
dbSNP Gene:8242 KDM5C
ENSEMBL:ENSG00000126012 KDM5C
HGNC:11114 KDM5C
Monarch:8242 KDM5C
NCBI Gene:8242 KDM5C
OMIM:314690 KDM5C
UCSC:P41229 KDM5C
Reference Transcript
RefSeq:XM_011530826.2 KDM5C
RefSeq:NM_004187.3 KDM5C
RefSeq:NM_001146702.1 KDM5C
RefSeq:XM_005262035.4 KDM5C
RefSeq:NM_001282622.1 KDM5C
Other Identifiers
11729141_at
11729142_a_at
11729143_at
11729144_x_at
11751930_a_at
11751931_x_at
11761133_at
17111149
202383_PM_at
202383_at
239207_PM_at
239207_at
33268_at
4009074
4009078
4009082
4009083
4009084
4009085
4009086
4009087
4009088
4009089
4009090
4009091
4009092
4009094
4009095
4009096
4009097
4009098
4009099
4009100
4009101
4009102
4009103
4009104
4009105
4009106
4009107
4009108
4009109
4009110
4009111
4009112
4009113
4009114
4009115
4009116
4009117
4009120
4009122
4009123
4009124
4009125
4009126
4009127
4009128
4009129
4009130
4009132
4009133
4009134
4009135
4009136
4009137
4009139
4009140
4009166
47205_at
54450_at
8172827
8242
A_23_P62270
A_33_P3216357
GE57689
GO:0000785
GO:0003677
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006325
GO:0006338
GO:0006355
GO:0008168
GO:0008270
GO:0009636
GO:0016491
GO:0016740
GO:0032259
GO:0032452
GO:0032453
GO:0034647
GO:0043226
GO:0045892
GO:0046872
GO:0048511
GO:0051213
GO:0140096
GO:0141052
HMNXSV003030643
HMNXSV003053271
Hs.96899.0.A1_3p_at
ILMN_1798224
L25270_at
PH_hs_0022253
TC0X001061.hg
g11321604_3p_at
Participates
as a member of
KDM5A-D [nucleoplasm] (Homo sapiens)
Inferred To
KDM5C [nucleoplasm]
(Bos taurus)
KDM5C [nucleoplasm]
(Caenorhabditis elegans)
KDM5C [nucleoplasm]
(Canis familiaris)
KDM5C [nucleoplasm]
(Mus musculus)
KDM5C [nucleoplasm]
(Saccharomyces cerevisiae)
KDM5C [nucleoplasm]
(Schizosaccharomyces pombe)
KDM5C [nucleoplasm]
(Sus scrofa)
Kdm5c [nucleoplasm]
(Rattus norvegicus)
rbbB [nucleoplasm]
(Dictyostelium discoideum)
Cross References
Guide to Pharmacology - Targets
2682
ENSEMBL
ENSP00000364550
,
ENSP00000385394
,
ENSP00000364532
,
ENSP00000445176
,
ENST00000404049
,
ENST00000375383
,
ENST00000452825
,
ENST00000375401
,
ENSP00000364528
,
ENST00000375379
OpenTargets
ENSG00000126012
ZINC - Substances
KDM5C_HUMAN
ZINC - Biogenic
KDM5C_HUMAN
ZINC target
P41229
PRO
P41229
GlyGen
P41229
PDB
5FWJ
,
2JRZ
ZINC - Metabolites
KDM5C_HUMAN
IntEnz
1.14.11.67
HPA
ENSG00000126012-KDM5C
Pharos - Targets
P41229
Orphanet
KDM5C
ZINC - Predictions - Purchasable
KDM5C_HUMAN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75461 E2F6
2
E2F6 [nucleoplasm]
(R-HSA-8953089)
p-S12-E2F6 [nucleoplasm]
(R-HSA-9007536)
0.597
3
UniProt:Q13127 REST
1
REST [nucleoplasm]
(R-HSA-480506)
0.558
3
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