SUMOyation of DNMT1 with SUMO1

Stable Identifier
R-HSA-4655431
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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SUMOyation of DNMT1 with SUMO1
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DNMT1 is SUMOyated at several unknown lysine residues with SUMO1 (Lee et al. 2009). SUMOylation increases the DNA methyltransferase activity of DNMT1.
Literature References
PubMed ID Title Journal Year
19450230 SUMOylation enhances DNA methyltransferase 1 activity

Lee, B, Muller, MT

Biochem. J. 2009
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Output
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as an event of
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]

Physical Entity
SUMO1:C93-UBE2I [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
SUMOyation of DNMT1 with SUMO1 (Bos taurus)
SUMOyation of DNMT1 with SUMO1 (Gallus gallus)
SUMOyation of DNMT1 with SUMO1 (Mus musculus)
SUMOyation of DNMT1 with SUMO1 (Rattus norvegicus)
SUMOyation of DNMT1 with SUMO1 (Sus scrofa)
SUMOyation of DNMT1 with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-09-28)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-10-03)
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