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AcK13-HIST1H2BK [nucleoplasm]
Stable Identifier
R-HSA-4568723
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H2B K
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
CREBBP acetylates histone H2B, H3, H4 (Homo sapiens)
AcK-histone H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK13-replicative histone H2B [nucleoplasm] (Homo sapiens)
Ack13-replicative histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
Delayed Early (DE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
Immediate Early (IE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
Transcriptional Activation of the HCMV Genome (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
HCMV Late Events (Homo sapiens)
Late (L) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
AcK13-HIST1H2BK [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60814 H2BC12
Gene Names
H2BC12, H2BFT, HIRIP1, HIST1H2BK
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:85236 H2BC12
CTD Gene:85236 H2BC12
dbSNP Gene:85236 H2BC12
ENSEMBL:ENSG00000197903 HIST1H2BK
ENSEMBL_homo_sapiens_GENE:ENSG00000197903.8 H2BC12
HGNC:13954 H2BC12
KEGG Gene (Homo sapiens):85236 H2BC12
Monarch:85236 H2BC12
NCBI Gene:85236 H2BC12
OMIM:615045 H2BC12
UCSC:O60814 H2BC12
Reference Transcript
RefSeq:NM_080593.2 H2BC12
RefSeq:NM_001312653.1 H2BC12
Other Identifiers
17016457
208579_PM_x_at
208579_x_at
2946721
2946722
35576_f_at
36347_f_at
3923212
3923213
8068898
85236
A_33_P3229083
GE553273
GO:0000786
GO:0002227
GO:0002376
GO:0003674
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0019731
GO:0030527
GO:0031640
GO:0042742
GO:0043226
GO:0043229
GO:0046982
GO:0050829
GO:0050830
GO:0061844
GO:0098542
HMNXSV003040333
ILMN_1813314
PH_hs_0037388
TC06001387.hg
TC06001388.hg
TC21000211.hg
TC21000762.hg
Participates
as a member of
Ack13-replicative histone HIST1H2B [nucleoplasm] (Homo sapiens)
as a candidate of
AcK(6,13,16,21)-HIST1H2BK [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-HIST1H2BK [nucleoplasm]
AcK-HIST1H2BK [nucleoplasm]
HIST1H2BK [extracellular region]
AcK6-HIST1H2BK [nucleoplasm]
AcK16-HIST1H2BK [nucleoplasm]
AcK21-HIST1H2BK [nucleoplasm]
Ub-121-HIST1H2BK [nucleoplasm]
HIST1H2BK [nucleoplasm]
Inferred To
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of AcK13-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of AcK13-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
Homologues of AcK13-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
AcK13-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
H2B-I [nucleoplasm]
(Gallus gallus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
H2AC12 [nucleoplasm]
(Bos taurus)
H2BC12 [nucleoplasm]
(Sus scrofa)
H2BC15 [nucleoplasm]
(Canis familiaris)
Homologues of AcK13-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of AcK13-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of AcK13-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.29 [nucleoplasm]
(Danio rerio)
AcK13-Histone H2B type 1-K [nucleoplasm]
(Mus musculus)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
AcK13-HIST1H2BC [nucleoplasm]
(Danio rerio)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
N6-acetyl-L-lysine at 13
Coordinate
13
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_001299582.1
,
NP_542160.1
OpenTargets
ENSG00000197903
HPA
ENSG00000197903-H2BC12
GeneCards
O60814
Ensembl
ENSP00000349430
,
ENST00000356950
,
ENSG00000197903
PRO
O60814
Pharos - Targets
O60814
PDB
7BWD
,
6T79
,
8JHG
,
6V92
,
7PF5
,
7PEY
,
7PF3
,
8Q3M
,
8GRQ
,
7V99
,
6T7D
,
7PFD
,
6T7B
,
7PFA
,
6Y5D
,
7V9J
,
7PFF
,
8WG5
,
8HQY
,
8IEJ
,
7XCR
,
7XD1
,
7PFV
,
7PFT
,
7PFX
,
6LE9
,
2CV5
,
7PEW
,
7JZV
,
7V90
,
7PF0
,
7PEU
,
8Q36
,
8JHF
,
7PF6
,
7PEZ
,
7V96
,
7PF4
,
7PEX
,
7VA4
,
6L9H
,
7DBP
,
8Q3E
,
6T7C
,
7PFC
,
8Q3X
,
7V9C
,
6T7A
,
7V9K
,
7PFE
,
7V9S
,
8IEG
,
7XCT
,
6KE9
,
7PFU
,
8HR1
,
7PFW
,
7PF2
,
7PEV
,
7PET
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