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AcK6-HIST1H2BM [nucleoplasm]
Stable Identifier
R-HSA-4568684
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
EP300 acetylates histone H2A, H2B, H3, H4 (Homo sapiens)
AcK-histone H2A, H2B, H3, H4 [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
HDACs deacetylate histones (Homo sapiens)
HDAC10 deacetylates histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
HDAC1:2-containing complex deacetylate histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
HDAC3 containing complexes deacetylate histone (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
HDAC8 deacetylates histones (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HCMV Infection (Homo sapiens)
HCMV Early Events (Homo sapiens)
Activation of Latent HCMV Genome (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
Delayed Early (DE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
Immediate Early (IE) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
Transcriptional Activation of the HCMV Genome (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
HCMV Late Events (Homo sapiens)
Late (L) Gene Expression (Homo sapiens)
Transcriptionally Active HCMV Genome [nucleoplasm] (Homo sapiens)
Acetylated core histone octamer [nucleoplasm] (Homo sapiens)
Acetylated histone H2A:H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)- histone H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-histone HIST1H2B [nucleoplasm] (Homo sapiens)
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
AcK6-HIST1H2BM [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99879 H2BC14
Gene Names
H2BC14, H2BFE, HIST1H2BM
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8342 H2BC14
CTD Gene:8342 H2BC14
dbSNP Gene:8342 H2BC14
ENSEMBL:ENSG00000273703 HIST1H2BM
ENSEMBL_homo_sapiens_GENE:ENSG00000273703.2 H2BC14
HGNC:4750 H2BC14
KEGG Gene (Homo sapiens):8342 H2BC14
Monarch:8342 H2BC14
NCBI Gene:8342 H2BC14
OMIM:602802 H2BC14
UCSC:Q99879 H2BC14
Reference Transcript
RefSeq:NM_003521.2 H2BC14
Other Identifiers
11733740_at
17005865
208515_PM_at
208515_at
2900060
2900061
31528_f_at
8117594
8342
ADDON002868.hg
A_24_P3783
GO:0000786
GO:0003677
GO:0005198
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0043229
GO:0046982
GO:0065003
GO:0070062
HMNXSV003032132
ILMN_1736820
PH_hs_0032040
TC06000265.hg
g4504262_3p_at
Participates
as a member of
AcK(6,13,16,21)-HIST1H2BM [nucleoplasm] (Homo sapiens)
Other forms of this molecule
Ub-HIST1H2BM [nucleoplasm]
AcK-HIST1H2BM [nucleoplasm]
HIST1H2BM [extracellular region]
AcK16-HIST1H2BM [nucleoplasm]
AcK21-HIST1H2BM [nucleoplasm]
AcK13-HIST1H2BM [nucleoplasm]
Ub-121-HIST1H2BM [nucleoplasm]
HIST1H2BM [nucleoplasm]
Inferred To
AcK6-HIST1H2BM [nucleoplasm]
(Bos taurus)
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
H2B-V [nucleoplasm]
(Gallus gallus)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of AcK6-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
H2B-I [nucleoplasm]
(Gallus gallus)
H2BC5 [nucleoplasm]
(Sus scrofa)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.29 [nucleoplasm]
(Danio rerio)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Plasmodium falciparum)
Homologues of AcK6-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
LOC119867718 [nucleoplasm]
(Canis familiaris)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
H2bc4 [nucleoplasm]
(Mus musculus)
LOC570661 [nucleoplasm]
(Danio rerio)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
N6-acetyl-L-lysine at 6
Coordinate
6
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_003512.1
OpenTargets
ENSG00000273703
HPA
ENSG00000273703-H2BC14
GeneCards
Q99879
Ensembl
ENSP00000477907
,
ENST00000621112
,
ENSG00000273703
PRO
Q99879
Pharos - Targets
Q99879
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