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TGIF2 [nucleoplasm]
Stable Identifier
R-HSA-452977
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Homeobox protein TGIF2, TGIF2_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Homo sapiens)
WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it (Homo sapiens)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by TGFB family members (Homo sapiens)
Signaling by TGF-beta Receptor Complex (Homo sapiens)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Homo sapiens)
WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it (Homo sapiens)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Homo sapiens)
TGIF [nucleoplasm] (Homo sapiens)
TGIF2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9GZN2 TGIF2
Gene Names
TGIF2
Chain
chain:1-237
Reference Genes
BioGPS Gene:60436 TGIF2
COSMIC (genes):TGIF2 TGIF2
CTD Gene:60436 TGIF2
dbSNP Gene:60436 TGIF2
ENSEMBL:ENSG00000118707 TGIF2
HGNC:15764 TGIF2
KEGG:hsa:60436 TGIF2
Monarch:60436 TGIF2
NCBI Gene:60436 TGIF2
OMIM:607294 TGIF2
UCSC:Q9GZN2 TGIF2
Reference Transcript
RefSeq:NM_021809.6 TGIF2
RefSeq:NM_001199515.1 TGIF2
RefSeq:NM_001199513.1 TGIF2
RefSeq:NM_001199514.1 TGIF2
Other Identifiers
11718929_a_at
11718930_a_at
216262_PM_s_at
216262_s_at
218724_PM_s_at
218724_s_at
38311_at
3883942
3883943
3883944
3883945
3883948
3883949
3883957
3883958
3883959
3883960
3883961
3883962
3883963
3883964
60436
8062319
85132_at
A_14_P115177
A_14_P136868
A_23_P79794
GE88340
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001227
GO:0003677
GO:0003700
GO:0005634
GO:0005654
GO:0005813
GO:0005815
GO:0006355
GO:0010470
GO:0030154
GO:0030182
GO:0035881
GO:0038092
GO:0043226
GO:0048856
GO:0060041
GO:0140110
GO:1902871
GO:1990837
HMNXSV003017101
Hs.94785.1.A1_3p_a_at
ILMN_1709044
PH_hs_0005182
TC20001729.hg
g11141880_3p_a_at
Participates
as a member of
TGIF [nucleoplasm] (Homo sapiens)
Inferred To
Tgif2 [nucleoplasm]
(Mus musculus)
TGIF2 [nucleoplasm]
(Bos taurus)
TGIF2 [nucleoplasm]
(Canis familiaris)
TGIF2 [nucleoplasm]
(Rattus norvegicus)
TGIF2 [nucleoplasm]
(Sus scrofa)
vis [nucleoplasm]
(Drosophila melanogaster)
ceh-57 [nucleoplasm]
(Caenorhabditis elegans)
achi [nucleoplasm]
(Drosophila melanogaster)
ceh-60 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of TGIF2 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of TGIF2 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_068581.1
,
NP_001186442.1
,
NP_001186444.1
,
NP_001186443.1
ENSEMBL
ENST00000560025
,
ENST00000373874
,
ENST00000611732
,
ENST00000650844
,
ENSP00000498657
,
ENSP00000362981
,
ENST00000373872
,
ENSP00000481787
,
ENSP00000362979
,
ENSP00000453773
OpenTargets
ENSG00000118707
HPA
ENSG00000118707-TGIF2
PRO
Q9GZN2
Pharos - Targets
Q9GZN2
GlyGen
Q9GZN2
HMDB Protein
HMDBP14462
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