Reactome | TGIF2 [nucleoplasm]

TGIF2 [nucleoplasm]

Stable Identifier

R-CFA-452977

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

TGIF2, A0A8I3PWZ5

Locations in the PathwayBrowser

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Gene expression (Transcription) (Canis familiaris)

- RNA Polymerase II Transcription (Canis familiaris)
  - Generic Transcription Pathway (Canis familiaris)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
        
        TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Canis familiaris)
        
        TGIF [nucleoplasm] (Canis familiaris)
        
        TGIF2 [nucleoplasm] (Canis familiaris)
        
        p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Canis familiaris)
        
        TGIF [nucleoplasm] (Canis familiaris)
        
        TGIF2 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by TGFB family members (Canis familiaris)
  - Signaling by TGF-beta Receptor Complex (Canis familiaris)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
      - Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
        
        TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Canis familiaris)
        
        TGIF [nucleoplasm] (Canis familiaris)
        
        TGIF2 [nucleoplasm] (Canis familiaris)
        
        p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Canis familiaris)
        
        TGIF [nucleoplasm] (Canis familiaris)
        
        TGIF2 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PWZ5

Gene Names

TGIF2

Reference Genes

BioGPS Gene:485857 TGIF2

ENSEMBL:ENSCAFG00845025985.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025985.1 TGIF2

KEGG Gene (Canis lupus familiaris):485857 TGIF2

Monarch:485857 TGIF2

NCBI Gene:485857 TGIF2

Reference Transcript

Other Identifiers

485857

CfaAffx.13539.1.S1_s_at

GO:0000122

GO:0003677

GO:0005634

GO:0005654

GO:0005813

GO:0005815

GO:0005856

GO:0006351

GO:0006355

GO:0010470

GO:0023052

GO:0030154

GO:0030182

GO:0035881

GO:0038092

GO:0043226

GO:0048856

GO:0060041

GO:1902871

GO:1990837

Participates

as a member of

TGIF [nucleoplasm] (Canis familiaris)

Inferred From

TGIF2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005635061.1, XP_013962378.1, XP_865618.1, XP_005635062.1, XP_005635060.1, XP_005635064.1, XP_005635063.1

OpenTargets

ENSG00000118707

Ensembl

ENSCAFG00845025985, ENSCAFT00845045854, ENSCAFP00845035999

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