Expression of DPPA4

Stable Identifier
Reaction [omitted]
Homo sapiens
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DPPA4 is expressed in pluripotent stem cells. The promoter of the DPPA4 gene binds OCT4 (POU5F1), SOX2, and NANOG (Player et al. 2006, Boyer et al. 2007, inferred from mouse homologs in Chakravarthy et al. 2008). OCT4 Knockdown experiments show OCT4 enhances expression of DPPA4 (Babaie et al. 2007).

Literature References
PubMed ID Title Journal Year
16153702 Core transcriptional regulatory circuitry in human embryonic stem cells

Boyer, LA, Lee, TI, Cole, MF, Johnstone, SE, Levine, SS, Zucker, JP, Guenther, MG, Kumar, RM, Murray, HL, Jenner, RG, Gifford, DK, Melton, DA, Jaenisch, R, Young, RA

Cell 2005
18366076 Identification of DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays

Chakravarthy, H, Boer, B, Desler, M, Mallanna, SK, McKeithan, TW, Rizzino, A

J Cell Physiol 2008
16846370 Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines

Player, A, Wang, Y, Bhattacharya, B, Rao, M, Puri, RK, Kawasaki, ES

Stem Cells Dev 2006
17068183 Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells

Babaie, Y, Herwig, R, Greber, B, Brink, TC, Wruck, W, Groth, D, Lehrach, H, Burdon, T, Adjaye, J

Stem Cells 2007
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