Caspase-1 active tetramer formation

Stable Identifier
R-HSA-448702
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Caspase-1 active tetramer formation
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Two p10/p20 dimers associate to form the active tetramer

Literature References
PubMed ID Title Journal Year
8044845 Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

Hackett, MC, Dang, LC, Franklin, S, Ghayur, T, Ferenz, CR, Walker, NP, Bump, NJ, Brady, KD, Talanian, RV, Hammill, LD

Cell 1994
Participants
Input
Output
Participates
as an event of
Orthologous Events
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Authored
Ray, KP  (2010-05-17)
Reviewed
Pinteaux, E  (2010-09-06)
Created
Jupe, S  (2009-11-25)
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