T1R2/T1R3 dimer is a sweet taste receptor

Stable Identifier
R-HSA-444606
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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A dimer of T1R2 and T1R3 receptors responds to diverse stimuli associated with the human sense of sweet taste, such as sucrose, d-tryptophan, aspartame, and saccharin. Signaling occurs via the Gi family G-protein Gustducin (Caicedo et al. 2003).

Literature References
PubMed ID Title Journal Year
11917125 Human receptors for sweet and umami taste

Li, X, Staszewski, L, Xu, H, Durick, K, Zoller, M, Adler, E

Proc Natl Acad Sci U S A 2002
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