T1R2/T1R3 dimer is a sweet taste receptor

Stable Identifier
R-HSA-444606
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane
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T1R2/T1R3 dimer is a sweet taste receptor
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A dimer of T1R2 and T1R3 receptors responds to diverse stimuli associated with the human sense of sweet taste, such as sucrose, d-tryptophan, aspartame, and saccharin. Signaling occurs via the Gi family G-protein Gustducin (Caicedo et al. 2003).

Literature References
PubMed ID Title Journal Year
11917125 Human receptors for sweet and umami taste

Li, X, Staszewski, L, Xu, H, Durick, K, Zoller, M, Adler, E

Proc Natl Acad Sci U S A 2002
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Orthologous Events
T1R2/T1R3 dimer is a sweet taste receptor (Danio rerio)
T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)
T1R2/T1R3 dimer is a sweet taste receptor (Rattus norvegicus)
T1R2/T1R3 dimer is a sweet taste receptor (Sus scrofa)
Authored
Jupe, S  (2009-10-23)
Reviewed
D'Eustachio, P  (2009-12-12)
Created
Jupe, S  (2009-10-26)