Zinc is an agonist of GPR39

Stable Identifier
R-HSA-444572
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Zn2+ is a potent and effective agonist of GPR39, signaling effectively through the Gq pathway (Holst et al. 2004, 2007) and Gs (Zhang et al. 2005, Holst et al. 2007).
Literature References
PubMed ID Title Journal Year
18588883 Molecular mechanism of Zn2+ agonism in the extracellular domain of GPR39

Storjohann, L, Holst, B, Schwartz, TW

FEBS Lett 2008
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!