Carrier-mediated urea transport allows rapid urea movement across the cell membrane, which is particularly important in the process of urinary concentration and for rapid urea equilibrium in non-renal tissues. Two carriers exist in humans, HUT2 which is renal-specific (Olives B et al, 1996) and HUT11, which is erythrocyte-specific (Olives B et al, 1994).
Olivès, B, Matassi, G, Bailly, P, Cartron, JP, Martial, S, Rousselet, G, Mattéi, MG, Ripoche, P
Olives, B, Cartron, JP, Bailly, P, Rousselet, G, Hediger, MA, Neau, P, Ripoche, P
urea transmembrane transporter activity of Urea transporters [plasma membrane]
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