Reactome | SLC39A8 [plasma membrane]

SLC39A8 [plasma membrane]

Stable Identifier

R-HSA-442328

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ZIP8, BIGM103, Zinc transporter ZIP8, S39A8_HUMAN

Locations in the PathwayBrowser

Expand all

Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
    - Metal ion SLC transporters (Homo sapiens)
      - Zinc transporters (Homo sapiens)
        
        Zinc influx into cells by the SLC39 gene family (Homo sapiens)
        
        ZIP8 mediates zinc influx into cells (Homo sapiens)
        
        SLC39A8-like proteins [plasma membrane] (Homo sapiens)
        
        SLC39A8 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9C0K1 SLC39A8

Gene Names

SLC39A8, BIGM103, ZIP8, PP3105

Chain

signal peptide:1-22, chain:23-460

Reference Genes

BioGPS Gene:64116 SLC39A8

COSMIC (genes):SLC39A8 SLC39A8

CTD Gene:64116 SLC39A8

dbSNP Gene:64116 SLC39A8

ENSEMBL:ENSG00000138821 SLC39A8

HGNC:20862 SLC39A8

KEGG:hsa:64116 SLC39A8

Monarch:64116 SLC39A8

NCBI Gene:64116 SLC39A8

OMIM:608732 SLC39A8

UCSC:Q9C0K1 SLC39A8

Reference Transcript

Other Identifiers

11724249_a_at

11724250_a_at

11724251_x_at

11724252_s_at

11734800_at

11740764_at

16978417

209266_PM_s_at

209266_s_at

209267_PM_s_at

209267_s_at

219869_PM_s_at

219869_s_at

222935_PM_x_at

222935_x_at

2779820

2779822

2779824

2779825

2779826

2779827

2779828

2779830

2779831

2779832

2779833

2779834

2779838

2779839

2779840

2779842

2779843

2779846

2779847

2779854

2779855

2779856

2779857

2779858

2779859

2779860

2779877

40456_at

64116

78153_at

8101992

90587_at

A_23_P41424

A_33_P3283824

GE56216

GO:0005215

GO:0005385

GO:0005764

GO:0005765

GO:0005773

GO:0005886

GO:0006351

GO:0006355

GO:0006486

GO:0006487

GO:0006520

GO:0006525

GO:0006824

GO:0006829

GO:0006882

GO:0007155

GO:0015293

GO:0015694

GO:0015701

GO:0016020

GO:0016323

GO:0016324

GO:0030001

GO:0030003

GO:0030026

GO:0030198

GO:0031090

GO:0042391

GO:0043124

GO:0043226

GO:0046873

GO:0050728

GO:0055085

GO:0061757

GO:0070574

GO:0071421

GO:0071577

GO:0071578

GO:0097080

GO:0098711

GO:0098754

GO:0098849

GO:0140410

GO:0140412

GO:1990079

GO:1990540

HMNXSV003000481

HMNXSV003012829

HMNXSV003038535

Hs.284205.0.S1_3p_a_at

Hs.284205.1.A1_3p_a_at

ILMN_1695316

ILMN_2233539

PH_hs_0014719

TC04002651.hg

TC04002924.hg

g11545899_3p_a_at

g12657580_3p_a_at

Participates

as a member of

SLC39A8-like proteins [plasma membrane] (Homo sapiens)

Inferred To

zipt-15 [plasma membrane] (Caenorhabditis elegans)

Slc39a8 [plasma membrane] (Mus musculus)

Slc39a8 [plasma membrane] (Rattus norvegicus)

SLC39A8 [plasma membrane] (Bos taurus)

SLC39A8 [plasma membrane] (Canis familiaris)

SLC39A8 [plasma membrane] (Gallus gallus)

SLC39A8 [plasma membrane] (Sus scrofa)

slc39a8 [plasma membrane] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

1187

ENSEMBL

ENST00000682227, ENSP00000508363, ENSP00000349174, ENSG00000138821, ENSP00000378310, ENST00000683412, ENST00000682932, ENST00000356736, ENSP00000507414, ENST00000394833, ENSP00000507538

OpenTargets

ENSG00000138821

GeneCards

SLC39A8

HPA

ENSG00000138821-SLC39A8

PRO

Q9C0K1

Pharos - Targets

Q9C0K1

GlyGen

Q9C0K1

Orphanet

SLC39A8

HMDB Protein

HMDBP11941