Reactome | SLC11A2 [plasma membrane]

SLC11A2 [plasma membrane]

Stable Identifier

R-HSA-435359

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

DCT1, NRAMP2, Natural resistance-associated macrophage protein 2, NRAM2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49281 SLC11A2

Gene Names

SLC11A2, DCT1, DMT1, NRAMP2, OK/SW-cl.20

Chain

chain:1-568

Reference Genes

BioGPS Gene:4891 SLC11A2

COSMIC - genes:SLC11A2 SLC11A2

CTD Gene:4891 SLC11A2

dbSNP Gene:4891 SLC11A2

ENSEMBL:ENSG00000110911 SLC11A2

HGNC:10908 SLC11A2

KEGG:hsa:4891 SLC11A2

Monarch:4891 SLC11A2

NCBI Gene:4891 SLC11A2

OMIM:600523 SLC11A2

UCSC:P49281 SLC11A2

Reference Transcript

Other forms of this molecule

SLC11A2 E399D [plasma membrane]

SLC11A2 V114del [plasma membrane]

SLC11A2 R416C [plasma membrane]

SLC11A2 L104_P142del [plasma membrane]

SLC11A2 G212V [plasma membrane]

Inferred To

Mvl [plasma membrane] (Drosophila melanogaster)

slc11a2 [plasma membrane] (Danio rerio)

slc11a2 [plasma membrane] (Xenopus tropicalis)

SLC11A2 [plasma membrane] (Bos taurus)

SLC11A2 [plasma membrane] (Canis familiaris)

SLC11A2 [plasma membrane] (Gallus gallus)

SLC11A2 [plasma membrane] (Sus scrofa)

Slc11a2 [plasma membrane] (Mus musculus)

Slc11a2 [plasma membrane] (Rattus norvegicus)

FVRT1 [plasma membrane] (Plasmodium falciparum)

nramp1 [plasma membrane] (Dictyostelium discoideum)

smf-1 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

XP_011536706.1, NP_001366375.1, NP_001366376.1, XP_054228099.1, XP_011536707.1, NP_001167600.1, XP_054228100.1, NP_000608.1, XP_054228101.1, NP_001167601.1, NP_001167596.1, NP_001167599.1, NP_001167597.1, XP_047284843.1, NP_001401675.1, NP_001401673.1, NP_001167598.1, NP_001401674.1, NP_001366384.1

Guide to Pharmacology - Targets

967

OpenTargets

ENSG00000110911

ENSEMBL

ENSP00000262052, ENSP00000449200, ENSP00000449008, ENST00000394904, ENST00000644495, ENSP00000444542, ENSP00000446769, ENSP00000378364, ENST00000547688, ENSP00000494107, ENST00000541174, ENST00000546636, ENSG00000110911, ENST00000547198, ENSP00000442810, ENST00000545993, ENST00000262052

ZINC - Substances

NRAM2_HUMAN

ZINC target

P49281

PRO

P49281

GlyGen

P49281

PDB

9F6N, 9F6O, 7BLO, 5F0L, 5F0P, 5F0M, 7BLQ

HPA

ENSG00000110911-SLC11A2

GeneCards

SLC11A2

Pharos - Targets

P49281

Orphanet

SLC11A2

ZINC - Predictions - Purchasable

NRAM2_HUMAN

HMDB Protein

HMDBP02405

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P23634 ATP2B4	1	ATP2B4 [plasma membrane] (R-HSA-418304)	0.527	2

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