SEMA7A binds to integrin alpha1beta1

Stable Identifier
R-HSA-434990
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Sema7A has a RGD-motif in the extracellular region and interacts with alpha1beta1 integrin in both olfactory nerves and monocytes/macrophages. This interaction stimulates cytokine production in monocytes and macrophages, and is critical for the effector phase of the inflammatory immune response.

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