SEMA7A binds to integrin alpha1beta1

Stable Identifier
R-HSA-434990
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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SEMA7A binds to integrin alpha1beta1
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Sema7A has a RGD-motif in the extracellular region and interacts with alpha1beta1 integrin in both olfactory nerves and monocytes/macrophages. This interaction stimulates cytokine production in monocytes and macrophages, and is critical for the effector phase of the inflammatory immune response.
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Inferred From
Sema7A binds integrin alpha1beta1 (Mus musculus)
Authored
Garapati, P V  (2009-03-23)
Reviewed
Kikutani, H  (2009-09-02)
Kumanogoh, A  (2009-09-02)
Created
Garapati, P V  (2009-09-04)
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