Reactome | SEMA7A [plasma membrane]

SEMA7A [plasma membrane]

Stable Identifier

R-HSA-198229

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Semaphorin 7A, SM7A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75326 SEMA7A

Gene Names

SEMA7A, CD108, SEMAL

Chain

signal peptide:1-44, chain:45-648, propeptide:649-666

Reference Genes

BioGPS Gene:8482 SEMA7A

COSMIC (genes):SEMA7A SEMA7A

CTD Gene:8482 SEMA7A

dbSNP Gene:8482 SEMA7A

ENSEMBL:ENSG00000138623 SEMA7A

HGNC:10741 SEMA7A

KEGG:hsa:8482 SEMA7A

Monarch:8482 SEMA7A

NCBI Gene:8482 SEMA7A

OMIM:607961 SEMA7A

UCSC:O75326 SEMA7A

Reference Transcript

Other Identifiers

11726571_a_at

11726572_a_at

11726573_a_at

11741755_a_at

16811638

210083_PM_at

210083_at

230345_PM_at

230345_at

3632908

3632909

3632910

3632911

3632913

3632914

3632916

3632917

3632918

3632919

3632921

3632922

3632923

3632924

3632925

3632935

3632936

3632937

41341_at

7990345

84610_at

8482

A_23_P106389

GE58306

GE819234

GO:0001649

GO:0001755

GO:0002376

GO:0005178

GO:0005515

GO:0005886

GO:0006954

GO:0006955

GO:0007229

GO:0007399

GO:0007411

GO:0009897

GO:0016020

GO:0021988

GO:0030154

GO:0030215

GO:0030312

GO:0030335

GO:0031012

GO:0031175

GO:0045499

GO:0045773

GO:0048018

GO:0048675

GO:0048856

GO:0048870

GO:0050727

GO:0050919

GO:0060907

GO:0062023

GO:0070374

GO:0071526

GO:0090128

GO:0098552

GO:0098772

GO:0098793

GO:0098982

HMNXSV003053561

Hs.170843.0.A1_3p_at

ILMN_1756312

PH_hs_0002166

PH_hs_0010222

TC15001643.hg

Participates

as a component of

as an input of

Inferred To

Sema2b [plasma membrane] (Drosophila melanogaster)

SEMA7A [plasma membrane] (Bos taurus)

SEMA7A [plasma membrane] (Canis familiaris)

SEMA7A [plasma membrane] (Gallus gallus)

SEMA7A [plasma membrane] (Sus scrofa)

mab-20 [plasma membrane] (Caenorhabditis elegans)

smp-1 [plasma membrane] (Caenorhabditis elegans)

Sema1b [plasma membrane] (Drosophila melanogaster)

Sema7a [plasma membrane] (Mus musculus)

Sema7a [plasma membrane] (Rattus norvegicus)

Sema1a [plasma membrane] (Drosophila melanogaster)

Homologues of SEMA7A [plasma membrane] (Caenorhabditis elegans)

Homologues of SEMA7A [plasma membrane] (Drosophila melanogaster)

Sema2a [plasma membrane] (Drosophila melanogaster)

smp-2 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001139502.1, NP_001139501.1, NP_003603.1

ENSEMBL

ENST00000543145, ENSP00000500204, ENST00000261918, ENSP00000500448, ENST00000672978, ENSP00000438966, ENST00000671713, ENSP00000261918

OpenTargets

ENSG00000138623

HPA

ENSG00000138623-SEMA7A

PRO

O75326

Pharos - Targets

O75326

PDB

3NVQ

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60486 PLXNC1	1	PLXNC1 [plasma membrane] (R-HSA-434899)	0.611	4
UniProt:Q2PZI1 D19L1			0.527	2
UniProt:Q9BXP2 S12A9			0.527	2
UniProt:P35610 SOAT1	1	SOAT1 [endoplasmic reticulum membrane] (R-HSA-8876490)	0.527	2
UniProt:Q9GZU3 TM39B			0.527	2
UniProt:P19634 SLC9A1	1	SLC9A1 [plasma membrane] (R-HSA-426006)	0.527	2
UniProt:Q6NUQ4 TM214			0.527	2
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.527	2
UniProt:Q07065 CKAP4	7	CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956737) p-CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956926) CKAP4 [azurophil granule membrane] (R-HSA-6799559) CKAP4 [plasma membrane] (R-HSA-5686306) CKAP4 [specific granule membrane] (R-HSA-6799552) PALM-C100-CKAP4 [plasma membrane] (R-HSA-5686280) PALM-C100-CKAP4 [lamellar body] (R-HSA-5686285)	0.527	2

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