TP53 (p53) binds the promoter of the PMAIP1 (NOXA) gene to induce PMAIP1 transcription (Oda et al. 2000, Li et al. 2004). TP53 likely associates with the PMAIP1 promoter as part of the complex with ASPP proteins PPP1R13B (ASPP1) or TP53BP2 (ASPP2) (Wang et al. 2012, Wilson et al. 2013).
Feinstein, E, Wilson, AM, Morquette, B, Abdouh, M, Bernier, G, Unsain, N, Di Polo, A, Barker, PA
Hanigan, CL, Robles, AI, Trudel, LJ, Hofseth, LJ, Li, CQ, Wogan, GN, Harris, CC
Taniguchi, T, Tokino, T, Yamashita, T, Shibue, T, Ohki, R, Oda, E, Nemoto, J, Murasawa, H, Tanaka, N
Tang, K, Tian, Z, Wang, L, Xing, H, Peng, L, Rao, Q, Wang, J, Li, Y, Wang, M
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