Activation of NOXA and translocation to mitochondria

Stable Identifier
R-HSA-111448
Type
Pathway
Species
Homo sapiens
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NOXA is transactivated in a p53-dependent manner and by E2F1. Activated NOXA is translocated to mitochondria.

Literature References
PubMed ID Title Journal Year
14684737 Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

Hershko, T, Ginsberg, D

J Biol Chem 2004
15126337 Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53

Hanigan, CL, Robles, AI, Trudel, LJ, Hofseth, LJ, Li, CQ, Wogan, GN, Harris, CC

Cancer Res 2004
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