Aquaporin-6 passively transports anions into vesicles

Stable Identifier
R-HSA-432034
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Aquaporin-6 (AQP6) passively transports anions across membranes. Rat AQP6 has been shown to transport anions, with the highest permeability for nitrate, the lowest permeability for fluoride, and low permeability for water. In rat AQP6 is expressed in the acid-secreting type-A intercalated cells of renal ducts where it co-localizes with the proton-ATPase in the membranes of intracellular vesicles. AQP6 is gated by low pH.

Literature References
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Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
anion channel activity of AQP6 tetramer [transport vesicle membrane]
Physical Entity
Activity
Inferred From
Cross References
Rhea
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