Proton-coupled histidine and di-peptide cotransport

Stable Identifier
R-HSA-428007
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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A bioinformatics approach identified two further human transporters, PHT1 and PHT2 (Botka CW et al, 2000). These two transporters may be located on the lysosomal membrane for the proton-coupled export of histidine and di-peptides from lysosomal protein degradation.

Literature References
PubMed ID Title Journal Year
11741232 Human proton/oligopeptide transporter (POT) genes: identification of putative human genes using bioinformatics

Botka, CW, Wittig, TW, Graul, RC, Nielsen, CU, Higaka, K, Amidon, GL, Sadee, W

AAPS PharmSci 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
peptide:proton symporter activity of PHT cotransporters [lysosomal membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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