Na+/H+ exchanger transport (at trans-golgi membrane)

Stable Identifier
R-HSA-426015
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi membrane
ReviewStatus
5/5
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Na+/H+ exchanger transport (at trans-golgi membrane)
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NHE7 and 8 (SLC9A7,8) (Nakamura N et al, 2005) are expressed ubiquitously and thought to play a housekeeping role in pH homeostasis in the trans-golgi network.
Literature References
PubMed ID Title Journal Year
11279194 Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network

Orlowski, J, Numata, M

J Biol Chem 2001
15522866 Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation

Mitsui, K, Tanaka, S, Teko, Y, Kanazawa, H, Nakamura, N

J Biol Chem 2005
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sodium:proton antiporter activity of SLC9A7/8 [Golgi membrane]

Physical Entity
SLC9A7/8 [Golgi membrane] (Homo sapiens)
Activity
sodium:proton antiporter activity (GO:0015385)
Orthologous Events
Na+/H+ exchanger transport (at trans-golgi membrane) (Bos taurus)
Na+/H+ exchanger transport (at trans-golgi membrane) (Caenorhabditis elegans)
Na+/H+ exchanger transport (at trans-golgi membrane) (Canis familiaris)
Na+/H+ exchanger transport (at trans-golgi membrane) (Danio rerio)
Na+/H+ exchanger transport (at trans-golgi membrane) (Dictyostelium discoideum)
Na+/H+ exchanger transport (at trans-golgi membrane) (Drosophila melanogaster)
Na+/H+ exchanger transport (at trans-golgi membrane) (Gallus gallus)
Na+/H+ exchanger transport (at trans-golgi membrane) (Mus musculus)
Na+/H+ exchanger transport (at trans-golgi membrane) (Rattus norvegicus)
Na+/H+ exchanger transport (at trans-golgi membrane) (Saccharomyces cerevisiae)
Na+/H+ exchanger transport (at trans-golgi membrane) (Schizosaccharomyces pombe)
Na+/H+ exchanger transport (at trans-golgi membrane) (Sus scrofa)
Na+/H+ exchanger transport (at trans-golgi membrane) (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2009-06-11)
Reviewed
He, L  (2009-08-24)
Created
Jassal, B  (2009-06-11)
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