Reactome | FAAP24 [cytosol]

FAAP24 [cytosol]

Stable Identifier

R-HSA-420798

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Fanconi anemia-associated protein of 24 kDa, FAP24_HUMAN

Locations in the PathwayBrowser

Expand all

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Interferon Signaling (Homo sapiens)
    - Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
      - PKR-mediated signaling (Homo sapiens)
        
        FA core complex:HSP70s binds PKR (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FANCM:FAAP24 [cytosol] (Homo sapiens)
        
        FAAP24 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FANCM:FAAP24 [cytosol] (Homo sapiens)
        
        FAAP24 [cytosol] (Homo sapiens)
        
        PKR forms a dimer (Homo sapiens)
        
        FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Homo sapiens)
        
        FA Core Complex:HSP70s [cytosol] (Homo sapiens)
        
        FA Core Complex [cytosol] (Homo sapiens)
        
        FANCM:FAAP24 [cytosol] (Homo sapiens)
        
        FAAP24 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BTP7 FAAP24

Gene Names

FAAP24, C19orf40

Chain

chain:1-215

Reference Genes

BioGPS Gene:91442 FAAP24

COSMIC (genes):FAAP24 FAAP24

CTD Gene:91442 FAAP24

dbSNP Gene:91442 FAAP24

ENSEMBL:ENSG00000131944 FAAP24

HGNC:28467 FAAP24

KEGG:hsa:91442 FAAP24

Monarch:91442 FAAP24

NCBI Gene:91442 FAAP24

OMIM:610884 FAAP24

UCSC:Q9BTP7 FAAP24

Reference Transcript

Other Identifiers

11733191_at

16860580

214816_3p_x_at

214816_PM_x_at

214816_x_at

3829162

3829163

3829164

3829165

3829166

3829167

3829168

3829169

3829170

3829171

3829172

3829173

8027510

91442

A_23_P338505

GE579744

GO:0000785

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006281

GO:0036297

GO:0043226

GO:0043231

GO:0043240

GO:0071821

HMNXSV003048089

Hs.192127.0.S1_3p_x_at

ILMN_2173891

PH_hs_0011320

TC19000431.hg

Participates

as a component of

FANCM:FAAP24 [cytosol] (Homo sapiens)

Other forms of this molecule

FAAP24 [nucleoplasm]

Inferred To

Faap24 [cytosol] (Mus musculus)

Faap24 [cytosol] (Rattus norvegicus)

faap24 [cytosol] (Xenopus tropicalis)

FAAP24 [cytosol] (Bos taurus)

FAAP24 [cytosol] (Canis familiaris)

FAAP24 [cytosol] (Gallus gallus)

FAAP24 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_001287907.1, NP_689479.1

ENSEMBL

ENST00000699960, ENST00000588258, ENSP00000468475, ENSP00000466121, ENSP00000514718, ENST00000590281

OpenTargets

ENSG00000131944

HPA

ENSG00000131944-FAAP24

PRO

Q9BTP7

Pharos - Targets

Q9BTP7

GlyGen

Q9BTP7

PDB

2LYH, 2M9N, 2M9M, 4M6W, 4BXO

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IYD8 FANCM	3	FANCM [cytosol] (R-HSA-420802) p-S1045-FANCM [nucleoplasm] (R-HSA-6788401) FANCM [nucleoplasm] (R-HSA-419535)	0.752	12
IntAct:EBI-12506732 SPLAYED			0.602	3
IntAct:EBI-12506721 SPLAYED			0.544	2
IntAct:EBI-12506682 SS			0.544	2
UniProt:Q8IYD8-1 FANCM			0.522	2
UniProt:Q7Z6E9-3 RBBP6			0.488	2

Cite Us!