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SCTR [plasma membrane]
Stable Identifier
R-HSA-420097
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Secretin receptor, SCTR_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
Secretin receptor binds secretin (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCTR [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P47872 SCTR
Gene Names
SCTR
Chain
signal peptide:1-22, chain:23-440
Reference Genes
BioGPS Gene:6344 SCTR
COSMIC (genes):SCTR SCTR
CTD Gene:6344 SCTR
dbSNP Gene:6344 SCTR
ENSEMBL:ENSG00000080293 SCTR
HGNC:10608 SCTR
KEGG:hsa:6344 SCTR
Monarch:6344 SCTR
NCBI Gene:6344 SCTR
OMIM:182098 SCTR
UCSC:P47872 SCTR
Reference Transcript
RefSeq:NM_002980.2 SCTR
Other Identifiers
11725010_a_at
16902233
210382_PM_at
210382_at
2573113
2573114
2573115
2573116
2573118
2573119
2573123
2573124
2573125
2573129
2573130
2573132
2573134
2573135
2573136
2573143
2573144
2573150
2573151
32902_at
6344
8054846
A_23_P28139
GE59048
GO:0002024
GO:0004888
GO:0004930
GO:0005881
GO:0005886
GO:0007166
GO:0007186
GO:0007188
GO:0007189
GO:0008528
GO:0009992
GO:0015055
GO:0016020
GO:0017046
GO:0031667
GO:0032098
GO:0048167
GO:0060089
HMNXSV003029902
ILMN_1772537
PH_hs_0024201
TC02002254.hg
U28281_at
g763533_3p_at
Participates
as an input of
Secretin receptor binds secretin (Homo sapiens)
as a member of
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
as a component of
SCTR:SCT [plasma membrane] (Homo sapiens)
Inferred To
Sctr [plasma membrane]
(Mus musculus)
Sctr [plasma membrane]
(Rattus norvegicus)
SCTR [plasma membrane]
(Bos taurus)
SCTR [plasma membrane]
(Canis familiaris)
SCTR [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_002971.2
Guide to Pharmacology - Targets
252
ENSEMBL
ENSP00000019103
,
ENST00000019103
OpenTargets
ENSG00000080293
HPA
ENSG00000080293-SCTR
ZINC - Substances
SCTR_HUMAN
ZINC target
P47872
PRO
P47872
Pharos - Targets
P47872
GlyGen
P47872
PDB
6WI9
,
7D3S
,
6WZG
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