PKG1 phosphorylates BK channels

Stable Identifier
R-HSA-418549
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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PKG1 phosphorylates BK channels
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NO-induced activation of cGMP-dependent protein kinase (PKG) increases the open probability of large conductance Ca2+-activated K+ channels (BK channels) by direct phosphorylation.
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Catalyst Activity

cGMP-dependent protein kinase activity of Cyclic GMP-dependent protein kinases (PKGs) [cytosol]

Physical Entity
Cyclic GMP-dependent protein kinases (PKGs) [cytosol] (Homo sapiens)
Activity
cGMP-dependent protein kinase activity (GO:0004692)
Inferred From
PKG1a phosphorylates BK channels (Bos taurus)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-04-23)
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