PDE10A [cytosol]

Stable Identifier
R-HSA-418536
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Phosphodiesterase 10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, PDE10_HUMAN
Locations in the PathwayBrowser
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General

Can hydrolyze both cAMP and cGMP

External Reference Information
External Reference
UniProt:Q9Y233 PDE10A
Gene Names
PDE10A
Chain
chain:1-779
Reference Genes
BioGPS Gene:10846 PDE10A
COSMIC (genes):PDE10A PDE10A
CTD Gene:10846 PDE10A
dbSNP Gene:10846 PDE10A
ENSEMBL:ENSG00000112541 PDE10A
HGNC:8772 PDE10A
KEGG Gene (Homo sapiens):10846 PDE10A
Monarch:10846 PDE10A
NCBI Gene:10846 PDE10A
OMIM:610652 PDE10A
UCSC:Q9Y233 PDE10A
Reference Transcript
Other Identifiers
0003520333
10846
11736799_a_at
11736800_a_at
11741718_a_at
11755666_a_at
17025523
1LRB
205501_at
211170_s_at
211171_s_at
2984277
2984278
2984279
2984280
2984281
2984282
2984283
2984286
2984287
2984290
2984297
2984300
2984303
2984304
2984305
2984306
2984308
2984310
2984312
2984313
2984314
2984315
2984316
2984319
2984320
2984323
2984332
2984333
2984341
2984342
2984363
2984364
2OUN
2OUP
2OUQ
2OUR
2OUS
2OUU
2OUV
2OUY
2WEY
2Y0J
2ZMF
35522_at
3SN7
3SNI
3SNL
3UI7
3UUO
3WI2
3WS8
3WS9
3WYK
3WYL
3WYM
45998
47200
4AEL
4AJD
4AJF
4AJG
4AJM
4BBX
4DDL
4DFF
4FCB
4FCD
4HEU
4HF4
4LKQ
4LLJ
4LLK
4LLP
4LLX
4LM0
4LM1
4LM2
4LM3
4LM4
4MRW
4MRZ
4MS0
4MSA
4MSC
4MSE
4MSH
4MSN
4MUW
4MVH
4P0N
4P1R
4PHW
4TPM
4TPP
4WN1
4XY2
4YQH
4YS7
4ZO5
5AXP
5AXQ
5B4K
5B4L
5C1W
5C28
5C29
5C2A
5C2E
5C2H
5DH4
5DH5
5EDE
5EDG
5EDH
5EDI
5I2R
5K9R
5UWF
5XUI
5XUJ
5ZNL
6IJH
6IJI
6MSA
6MSC
76100_at
8130674
90632
A0A087WUD0
A0A1B1UZQ1
A0A1B1UZR0
A0A3B3IRU7
A0A3B3IS50
A0A3B3ISJ6
A0A3B3IU85
A0A3F2YP58
A_23_P356677
AAD32595
AAD32596
AAI04859
AAI04861
AB020593
AB026816
AB041798
AF127479
AF127480
AL117345
AL136130
AL160160
ANW09720
BAA78034
BAA84467
BAB16383
BC104858
BC104860
CAB045998
CAG38804
CCDS47513
CCDS5289
CH471051
CR536567
EAW47546
ENSG00000112541
ENSP00000355847
ENSP00000497426
ENST00000366882
ENST00000366882.6
ENST00000650117
ENST00000650117.1
EntrezGene:10846
EntrezGene:90632
EntrezGene:LINC00473
EntrezGene:PDE10A
g5902441_3p_a_at
GE53519
GE663759
GO:0000166
GO:0003674
GO:0003824
GO:0004112
GO:0004114
GO:0004118
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005829
GO:0006198
GO:0007165
GO:0007186
GO:0008081
GO:0008150
GO:0008152
GO:0009056
GO:0009058
GO:0010738
GO:0010754
GO:0016020
GO:0016787
GO:0030552
GO:0030553
GO:0034641
GO:0034655
GO:0043025
GO:0043167
GO:0043204
GO:0043949
GO:0043951
GO:0044281
GO:0046069
GO:0046872
GO:0047555
HGNC:8772
HPA047200
Hs.128291.0.S2_3p_at
Hs.128291.1.S2_3p_a_at
ILMN_1782955
ILMN_2121272
IPR002073
IPR003018
IPR003607
IPR023088
IPR023174
IPR029016
IPR036971
KU519414
LINC00473
MIM:610652
MIM:616921
MIM:616922
NM_001130690
NM_006661
NP_001124162
NP_006652
PDE10A
PDE10A-201
PDE10A-223
PF00233
PF01590
PH_hs_0016826
PH_hs_0025054
PR00387
SM00065
SM00471
TC06002297.hg
TC06003988.hg
UPI0000039E34
UPI000006F80E
XM_011535388
XM_024446311
XP_011533690
XP_024302079
Participant Of
hasMember
Inferred To
Homologues of PDE10A [cytosol] (Dictyostelium discoideum)
Homologues of PDE10A [cytosol] (Plasmodium falciparum)
PDE10A [cytosol] (Bos taurus)
PDE10A [cytosol] (Caenorhabditis elegans)
PDE10A [cytosol] (Canis familiaris)
PDE10A [cytosol] (Danio rerio)
PDE10A [cytosol] (Dictyostelium discoideum)
PDE10A [cytosol] (Gallus gallus)
PDE10A [cytosol] (Mus musculus)
PDE10A [cytosol] (Plasmodium falciparum)
PDE10A [cytosol] (Rattus norvegicus)
PDE10A [cytosol] (Sus scrofa)
PDE10A [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
IntEnz
GeneCards
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein