Reactome | PDE10A [cytosol]

PDE10A [cytosol]

Stable Identifier

R-RNO-418536

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

Q9QYJ6

Locations in the PathwayBrowser

Expand all

Hemostasis (Rattus norvegicus)

- Platelet homeostasis (Rattus norvegicus)
  - Nitric oxide stimulates guanylate cyclase (Rattus norvegicus)
    - cGMP effects (Rattus norvegicus)
      - cGMP is degraded by PDEs (Rattus norvegicus)
        
        cGMP phosphodiesterases [cytosol] (Rattus norvegicus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)
        
        PDE10A [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (s) signalling events (Rattus norvegicus)
      - cAMP degradation by Phosphodiesterases (Rattus norvegicus)
        
        cAMP PDEs [cytosol] (Rattus norvegicus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)
        
        PDE10A [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q9QYJ6

Reference Genes

BioGPS Gene:63885

ENSEMBL:ENSRNOG00000011310

ENSEMBL:ENSRNOG00000011310.9

ENSEMBL:ENSRNOG00055028570

ENSEMBL:ENSRNOG00060010248

ENSEMBL:ENSRNOG00065029728

KEGG Gene (Rattus norvegicus):63885

Monarch:63885

NCBI Gene:63885

Reference Transcript

RefSeq:NM_022236.1

Other Identifiers

10718043

1368438_at

1370669_a_at

17628570

5625837

5666365

5697356

5713441

5714377

5752422

5798294

5819433

5835662

5903829

5914502

5921428

5979487

5985102

6076894

6126348

6153282

6244586

6279270

6280030

6294114

6296595

6300936

6329565

6346746

6382295

63885

6461699

6476448

6521290

6527930

6615165

6625205

6657768

6660615

6686013

6732918

A_42_P584045

A_64_P031910

GE1171049

GE13095

GO:0003824

GO:0004114

GO:0005515

GO:0007165

GO:0008081

GO:0016787

GO:0023052

ILMN_1361915

Participates

as a member of

Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Rattus norvegicus)

Inferred From

PDE10A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_071572.1

ZINC target

Q9QYJ6

Ensembl

ENSRNOP00000042134, ENSRNOP00000060834, ENSRNOT00000111873, ENSRNOG00000011310, ENSRNOP00000091632, ENSRNOT00000067142, ENSRNOT00000043474

PRO

Q9QYJ6

RGD

68434

PDB

2OVV, 3QPO, 2O8H, 3HQY, 3QPN, 3HQZ, 2OVY, 3QPP, 3HQW, 6K9U, 3LXG, 3HR1

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