Reactome | DAPK3 [cytosol]

DAPK3 [cytosol]

Stable Identifier

R-HSA-418265

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Death-associated protein kinase 3, DAPK3_HUMAN

Locations in the PathwayBrowser

Expand all

Programmed Cell Death (Homo sapiens)

- Apoptosis (Homo sapiens)
  - Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
    - Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)
      - DAPK binds UNC5B (Homo sapiens)
        
        DAPKs [cytosol] (Homo sapiens)
        
        DAPK3 [cytosol] (Homo sapiens)
        
        Unc5B with death domain:DAPK [cytosol] (Homo sapiens)
        
        DAPKs [cytosol] (Homo sapiens)
        
        DAPK3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:O43293 DAPK3

Gene Names

DAPK3, ZIPK

Chain

chain:1-454

Reference Genes

BioGPS Gene:1613 DAPK3

COSMIC (genes):DAPK3 DAPK3

CTD Gene:1613 DAPK3

dbSNP Gene:1613 DAPK3

ENSEMBL:ENSG00000167657 DAPK3

HGNC:2676 DAPK3

KEGG Gene (Homo sapiens):1613 DAPK3

Monarch:1613 DAPK3

NCBI Gene:1613 DAPK3

OMIM:603289 DAPK3

UCSC:O43293 DAPK3

Reference Transcript

Other Identifiers

0003800301

11722399_a_at

11722400_a_at

1613

16867197

203890_s_at

203891_s_at

33903_at

3846508

3846509

3846511

3846513

3846516

3846517

3846518

3846522

3846523

3846529

3846530

3846532

3846533

8032718

A_23_P165028

A_33_P3224045

GE53147

GO:0000166

GO:0000278

GO:0000902

GO:0002376

GO:0003674

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005856

GO:0005884

GO:0006325

GO:0006355

GO:0006412

GO:0006417

GO:0006464

GO:0006468

GO:0006914

GO:0006915

GO:0006940

GO:0006950

GO:0007010

GO:0007049

GO:0007088

GO:0007155

GO:0007165

GO:0007267

GO:0007346

GO:0008022

GO:0008134

GO:0008140

GO:0008150

GO:0008219

GO:0008360

GO:0009056

GO:0009058

GO:0010506

GO:0016301

GO:0016310

GO:0016605

GO:0016740

GO:0017148

GO:0019899

GO:0022607

GO:0030154

GO:0030182

GO:0030335

GO:0031267

GO:0034330

GO:0034641

GO:0035556

GO:0040011

GO:0042802

GO:0042803

GO:0042981

GO:0043065

GO:0043167

GO:0043226

GO:0043519

GO:0043522

GO:0045121

GO:0046777

GO:0048856

GO:0048870

GO:0051276

GO:0051893

GO:0071346

GO:0090263

GO:0097190

GO:0106310

GO:0106311

GO:0140014

GO:2000145

GO:2000249

GO:2001241

HMNXSV003003374

Hs.25619.0.A1_3p_a_at

ILMN_1792710

PH_hs_0027888

TC19001053.hg

g4557510_3p_a_at

Participates

as a candidate of

DAPKs [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001339.1, XP_005259565.1

ZINC - World Drugs

DAPK3_HUMAN

Guide to Pharmacology - Targets

2004

OpenTargets

ENSG00000167657

ZINC - FDA approved

DAPK3_HUMAN

ZINC - Substances

DAPK3_HUMAN

ZINC - Biogenic

DAPK3_HUMAN

ZINC target

O43293

PRO

O43293

PDB

5VJA, 1YRP, 5A6O, 3BQR, 5A6N, 2J90, 3BHY

ZINC - Investigational

DAPK3_HUMAN

HPA

ENSG00000167657-DAPK3

GeneCards

O43293

Ensembl

ENSP00000301264, ENST00000545797, ENSG00000167657, ENST00000301264, ENSP00000442973

Pharos - Targets

O43293

Orphanet

24455

ZINC - Predictions - Purchasable

DAPK3_HUMAN

HMDB Protein

HMDBP01144