Reactome | Nuclear CMP-Neu5Ac translocates to cytosol

Nuclear CMP-Neu5Ac translocates to cytosol

Stable Identifier

R-HSA-4084990

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

nucleoplasm, cytosol

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        Nuclear CMP-Neu5Ac translocates to cytosol (Homo sapiens)

General

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Nuclear CMP-Neu5Ac translocates to cytosol

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Once CMP-N-acetylneuraminate (CMP-Neu5Ac) is formed, it leaves the nucleus through nuclear pores to be further modified or used in conjugation reactions in the Golgi apparatus (Li & Chen 2012). The mechanism of translocation is unknown.

Literature References