Reactome | CMP-Neu5Ac [nucleoplasm]

CMP-Neu5Ac [nucleoplasm]

Stable Identifier

R-ALL-4085418

Type

Chemical Compound [SimpleEntity]

Compartment

nucleoplasm

Synonyms

CMP-N-acetyl-beta-neuraminate(2-), CMP-N-acetylneuraminate, CMP-N-acetyl-beta-neuraminic acid

Locations in the PathwayBrowser

for Species:

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
      - Synthesis of substrates in N-glycan biosythesis (Bos taurus)
        
        Sialic acid metabolism (Bos taurus)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Bos taurus)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
      - Synthesis of substrates in N-glycan biosythesis (Canis familiaris)
        
        Sialic acid metabolism (Canis familiaris)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Canis familiaris)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Danio rerio)

- Post-translational protein modification (Danio rerio)
  - Asparagine N-linked glycosylation (Danio rerio)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
      - Synthesis of substrates in N-glycan biosythesis (Danio rerio)
        
        Sialic acid metabolism (Danio rerio)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Danio rerio)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Asparagine N-linked glycosylation (Gallus gallus)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
      - Synthesis of substrates in N-glycan biosythesis (Gallus gallus)
        
        Sialic acid metabolism (Gallus gallus)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Gallus gallus)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Asparagine N-linked glycosylation (Mus musculus)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
      - Synthesis of substrates in N-glycan biosythesis (Mus musculus)
        
        Sialic acid metabolism (Mus musculus)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Mus musculus)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
      - Synthesis of substrates in N-glycan biosythesis (Rattus norvegicus)
        
        Sialic acid metabolism (Rattus norvegicus)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Rattus norvegicus)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
      - Synthesis of substrates in N-glycan biosythesis (Sus scrofa)
        
        Sialic acid metabolism (Sus scrofa)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Sus scrofa)
        
        CMP-Neu5Ac [nucleoplasm]

Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - Asparagine N-linked glycosylation (Xenopus tropicalis)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
      - Synthesis of substrates in N-glycan biosythesis (Xenopus tropicalis)
        
        Sialic acid metabolism (Xenopus tropicalis)
        
        CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Xenopus tropicalis)
        
        CMP-Neu5Ac [nucleoplasm]

External Reference Information

External Reference

CMP-N-acetyl-beta-neuraminate(2-) [ChEBI:57812]

Participates

as an output of

as an input of

Nuclear CMP-Neu5Ac translocates to cytosol (Homo sapiens)

Other forms of this molecule

CMP-Neu5Ac [cytosol]

CMP-Neu5Ac [endoplasmic reticulum-Golgi intermediate compartment]

CMP-Neu5Ac [Golgi lumen]

Cross References

ZINC

000008215638

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