Reactome | FBXL3 [nucleoplasm]

FBXL3 [nucleoplasm]

Stable Identifier

R-HSA-400380

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

F-box/LRR-repeat protein 3, FBXL3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UKT7 FBXL3

Gene Names

FBXL3, FBL3A, FBXL3A

Chain

chain:1-428

Reference Genes

BioGPS Gene:26224 FBXL3

COSMIC (genes):FBXL3 FBXL3

CTD Gene:26224 FBXL3

dbSNP Gene:26224 FBXL3

ENSEMBL:ENSG00000005812 FBXL3

HGNC:13599 FBXL3

KEGG Gene (Homo sapiens):26224 FBXL3

Monarch:26224 FBXL3

NCBI Gene:26224 FBXL3

OMIM:605653 FBXL3

UCSC:Q9UKT7 FBXL3

Reference Transcript

Other Identifiers

11717982_a_at

11758250_s_at

16779844

225132_at

26224

3518463

3518464

3518465

3518466

3518467

3518468

3518469

3518470

3518475

3518476

3518477

3518480

3518485

3518486

3518492

3518493

3518494

3518495

54900_at

62716_at

78141_at

7972062

83645_at

GE54837

GE858911

GO:0000086

GO:0000151

GO:0000209

GO:0000278

GO:0003674

GO:0004842

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006464

GO:0007049

GO:0008150

GO:0009056

GO:0016567

GO:0016604

GO:0019005

GO:0031146

GO:0031648

GO:0032991

GO:0042752

GO:0043153

GO:0043161

GO:0043226

GO:0043687

GO:0048511

GO:0051726

HMNXSV003039762

Hs.7540.0.S1_3p_at

ILMN_2071405

TC13000742.hg

Participates

as an output of

CRY proteins are ubiquitinylated (Homo sapiens)

as a component of

FBXL3:CRY [nucleoplasm] (Homo sapiens)

as an input of

FBXL3 binds phosphorylated CRY proteins (Homo sapiens)

Other forms of this molecule

FBXL3 [cytosol]

Cross References

RefSeq

NP_036290.1, XP_005266393.1

OpenTargets

ENSG00000005812

GeneCards

Q9UKT7

HPA

ENSG00000005812-FBXL3

Ensembl

ENSG00000005812, ENST00000355619, ENSP00000347834

PRO

Q9UKT7

Pharos - Targets

Q9UKT7

PDB

4I6J

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9R194 Cry2	4	p-Cry2 [cytosol] (R-MMU-508666) Cry2 [cytosol] (R-MMU-508614) ub-p-Cry2 [nucleoplasm] (R-MMU-517964) p-Cry2 [nucleoplasm] (R-MMU-508638)	0.78	13
UniProt:Q9WTX5 Skp1	2	Skp1 [nucleoplasm] (R-MMU-9008726) Skp1 [cytosol] (R-MMU-174150)	0.623	4
UniProt:P97784 Cry1	4	p-Cry1 [cytosol] (R-MMU-508644) ub-p-Cry1 [nucleoplasm] (R-MMU-517961) Cry1 [cytosol] (R-MMU-508637) p-Cry1 [nucleoplasm] (R-MMU-508662)	0.564	2
UniProt:Q86XR8-3 CEP57			0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.556	3
UniProt:Q9UJ68 MSRA	1	MSRA [cytosol] (R-HSA-5676904)	0.556	3
UniProt:Q16526 CRY1	4	CRY1 [cytosol] (R-HSA-400247) p-S-CRY1 [cytosol] (R-HSA-400270) Ub-p-S-CRY1 [nucleoplasm] (R-HSA-517931) p-S-CRY1 [nucleoplasm] (R-HSA-400340)	0.527	3
UniProt:P63209 SKP1			0.508	2

© 2022 Reactome

Cite Us!