Reactome | FARP2 [cytosol]

FARP2 [cytosol]

Stable Identifier

R-HSA-396935

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

RhoGEF and pleckstrin domain-containing protein 2 (FARP2), FARP2_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RAC1 GTPase cycle (Homo sapiens)
        
        RAC1 GEFs activate RAC1 (Homo sapiens)
        
        RAC1 GEFs [cytosol] (Homo sapiens)
        
        FARP2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:O94887 FARP2

Gene Names

FARP2, KIAA0793, PLEKHC3

Chain

chain:1-1054

Reference Genes

BioGPS Gene:9855 FARP2

COSMIC (genes):FARP2 FARP2

CTD Gene:9855 FARP2

dbSNP Gene:9855 FARP2

ENSEMBL:ENSG00000006607 FARP2

HGNC:16460 FARP2

KEGG:hsa:9855 FARP2

Monarch:9855 FARP2

NCBI Gene:9855 FARP2

OMIM:617586 FARP2

UCSC:O94887 FARP2

Reference Transcript

Other Identifiers

11743313_a_at

11749163_a_at

11760904_a_at

11760905_at

1554337_PM_at

1554337_at

16893482

204511_PM_at

204511_at

225652_PM_at

225652_at

242857_PM_at

242857_at

2536532

2536534

2536542

2536543

2536544

2536545

2536546

2536547

2536548

2536549

2536550

2536551

2536552

2536553

2536559

2536561

2536562

2536563

2536564

2536565

2536567

2536568

2536569

2536570

2536571

2536575

2536576

2536577

2536583

2536584

2536585

2536586

2536587

2536588

2536589

2536591

2536593

2536600

2536601

2536602

2536603

2536604

2536605

2536606

2536607

2536608

2536610

2536612

2536613

2536614

2536615

3316108

35188_at

3567745

3981510

4012453

63202_at

63327_at

79047_at

8049847

9855

A_14_P113440

A_14_P139315

A_23_P90855

A_24_P59485

A_24_P76759

A_33_P3350728

GE53493

GO:0005085

GO:0005737

GO:0005829

GO:0005856

GO:0007010

GO:0007155

GO:0008092

GO:0016322

GO:0016601

GO:0022405

GO:0030036

GO:0030154

GO:0030316

GO:0033623

GO:0043226

GO:0065003

GO:0071526

GO:0071800

GO:0098772

HMNXSV003014429

HMNXSV003047953

Hs.10490.0.A1_3p_at

Hs.311977.0.S1_3p_at

Hs2.301283.2.S1_3p_s_at

ILMN_2062687

PH_hs_0015530

TC02001478.hg

TC02001479.hg

TC02003940.hg

g7662309_3p_at

Participates

as a candidate of

RAC1 GEFs [cytosol] (Homo sapiens)

as a component of

as an input of

as an output of

Sema3A binds Nrp-1 bound to PlexinA (Homo sapiens)

Inferred To

FARP2 [cytosol] (Bos taurus)

FARP2 [cytosol] (Canis familiaris)

FARP2 [cytosol] (Gallus gallus)

FARP2 [cytosol] (Sus scrofa)

Farp2 [cytosol] (Mus musculus)

Farp2 [cytosol] (Rattus norvegicus)

Ghost homologue of FARP2 [cytosol] (Danio rerio)

Ghost homologue of FARP2 [cytosol] (Xenopus tropicalis)

Cdep [cytosol] (Drosophila melanogaster)

frm-3 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

XP_047302466.1, NP_001269913.1, NP_001269912.1, XP_054200737.1, NP_055623.1

ENSEMBL

ENST00000627550, ENSP00000264042, ENSG00000006607, ENST00000264042, ENSP00000486597, ENST00000373287, ENSP00000362384

OpenTargets

ENSG00000006607

GeneCards

FARP2

HPA

ENSG00000006607-FARP2

PRO

O94887

Pharos - Targets

O94887

HMDB Protein

HMDBP11476

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54105 CLNS1A	1	CLNS1A [cytosol] (R-HSA-191796)	0.527	2
UniProt:Q15287 RNPS1	2	RNPS1 [cytosol] (R-HSA-159256) RNPS1 [nucleoplasm] (R-HSA-156778)	0.527	2
UniProt:Q9Y6H6 KCNE3	1	KCNE3 [plasma membrane] (R-HSA-977536)	0.527	3
UniProt:P12273 PIP	1	PIP [extracellular region] (R-HSA-5252061)	0.527	2
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.527	2