Reactome | EFNA1(?-182) C-ter [plasma membrane]

EFNA1(?-182) C-ter [plasma membrane]

Stable Identifier

R-HSA-3928427

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

EFNA1 C-terminal fragment, Ephrin-A1

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Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - EPH-Ephrin signaling (Homo sapiens)
      - EPH-ephrin mediated repulsion of cells (Homo sapiens)
        
        ADAM10 cleaves EFNAs (Homo sapiens)
        
        EFNA C-terminal fragments [plasma membrane] (Homo sapiens)
        
        EFNA1(?-182) C-ter [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P20827 EFNA1

Gene Names

EFNA1, EPLG1, LERK1, TNFAIP4

Chain

signal peptide:1-18, chain:19-182, chain:19-, propeptide:183-205

Reference Genes

BioGPS Gene:1942 EFNA1

COSMIC (genes):EFNA1 EFNA1

CTD Gene:1942 EFNA1

dbSNP Gene:1942 EFNA1

ENSEMBL:ENSG00000169242 EFNA1

ENSEMBL_homo_sapiens_GENE:ENSG00000169242.12 EFNA1

HGNC:3221 EFNA1

KEGG Gene (Homo sapiens):1942 EFNA1

Monarch:1942 EFNA1

NCBI Gene:1942 EFNA1

OMIM:191164 EFNA1

UCSC:P20827 EFNA1

Reference Transcript

Other Identifiers

11716341_s_at

11754106_a_at

16671642

1942

202023_PM_at

202023_at

2360679

2360680

2360684

2360686

2360688

2360690

2360691

2360692

2360693

2360694

2360695

2360696

2360697

2360699

2360701

2360702

40425_at

7905929

A_23_P113005

A_23_P254512

GE57985

GO:0000122

GO:0001525

GO:0001934

GO:0003180

GO:0003183

GO:0003199

GO:0005102

GO:0005515

GO:0005576

GO:0005886

GO:0006351

GO:0006355

GO:0007155

GO:0007267

GO:0007411

GO:0010719

GO:0012501

GO:0014028

GO:0016020

GO:0016477

GO:0023052

GO:0030154

GO:0030163

GO:0030182

GO:0033628

GO:0034330

GO:0034446

GO:0036211

GO:0043409

GO:0043410

GO:0043535

GO:0045765

GO:0046875

GO:0048013

GO:0048856

GO:0048870

GO:0050730

GO:0050731

GO:0050770

GO:0050821

GO:0061002

GO:0061098

GO:0070244

GO:0098552

GO:1902004

GO:1902961

GO:1903051

HMNXSV003006092

ILMN_2371053

ILMN_2371055

M57730_at

PH_hs_0019033

TC01001288.hg

g4758245_3p_at

Participates

as a member of

EFNA C-terminal fragments [plasma membrane] (Homo sapiens)

Other forms of this molecule

EFNA1 (19-?) N-ter [extracellular region]

EFNA1 [plasma membrane]

Cross References

RefSeq

NP_004419.2, NP_872626.1

OpenTargets

ENSG00000169242

GeneCards

P20827

HPA

ENSG00000169242-EFNA1

Ensembl

ENST00000368407, ENST00000368406, ENSG00000169242, ENSP00000357392, ENSP00000357391

PRO

P20827

Pharos - Targets

P20827

PDB

3MBW, 3CZU, 3HEI

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