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EPHB1 (?-984) [plasma membrane]
Stable Identifier
R-HSA-3928402
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ephrin type-B receptor 1 ecNumber2.7.10.1/ecNumber, EPHB1_HUMAN, EPHB1
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
MMP2,9 cleave EPHB (Homo sapiens)
EPHB C-terminal fragments (CTF) [plasma membrane] (Homo sapiens)
EPHB1 (?-984) [plasma membrane] (Homo sapiens)
gamma-secretase cleaves EPHB2 (Homo sapiens)
EPHB C-terminal fragments (CTF) [plasma membrane] (Homo sapiens)
EPHB1 (?-984) [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P54762 EPHB1
Gene Names
EPHB1, ELK, EPHT2, HEK6, NET
Chain
signal peptide:1-17, chain:18-984
Reference Genes
BioGPS Gene:2047 EPHB1
COSMIC (genes):EPHB1 EPHB1
CTD Gene:2047 EPHB1
dbSNP Gene:2047 EPHB1
ENSEMBL:ENSG00000154928 EPHB1
HGNC:3392 EPHB1
KEGG:hsa:2047 EPHB1
Monarch:2047 EPHB1
NCBI Gene:2047 EPHB1
OMIM:600600 EPHB1
UCSC:P54762 EPHB1
Reference Transcript
RefSeq:NM_004441.4 EPHB1
Other Identifiers
11727656_s_at
11727657_at
11753520_s_at
11755617_s_at
11763796_at
11763797_s_at
16945958
2047
210753_PM_s_at
210753_s_at
211898_PM_s_at
211898_s_at
230425_PM_at
230425_at
2643608
2643609
2643610
2643611
2643640
2643654
2643655
2643656
2643665
2643684
2643692
2643700
2643701
2643702
2643703
2643704
2643706
2643707
2643708
2643709
2643710
2643713
2643714
2643718
2643719
2643720
2643724
2643735
2643737
2643738
2643739
2643740
2643747
2643749
34331_at
8082846
A_14_P101857
A_23_P166993
GE80071
GE88090
GO:0001525
GO:0001771
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005003
GO:0005005
GO:0005515
GO:0005524
GO:0005576
GO:0005737
GO:0005768
GO:0005783
GO:0005829
GO:0005886
GO:0006468
GO:0007155
GO:0007163
GO:0007169
GO:0007399
GO:0007411
GO:0008046
GO:0014719
GO:0016020
GO:0016740
GO:0021545
GO:0021631
GO:0021934
GO:0021952
GO:0022008
GO:0030010
GO:0030154
GO:0030424
GO:0030425
GO:0031290
GO:0031410
GO:0031589
GO:0031901
GO:0032433
GO:0042995
GO:0043226
GO:0044877
GO:0045121
GO:0046328
GO:0046777
GO:0048013
GO:0048593
GO:0048856
GO:0048870
GO:0050804
GO:0050965
GO:0051965
GO:0060089
GO:0060326
GO:0060996
GO:0060997
GO:0061351
GO:0070062
GO:0070372
GO:0098978
GO:0140096
GO:1902723
GO:1902725
HMNXSV003036138
Hs.78436.4.A1_3p_at
ILMN_1692261
L40636_at
PH_hs_0023363
TC03000730.hg
g2739207_3p_a_at
g2739209_3p_a_at
Participates
as a member of
EPHB C-terminal fragments (CTF) [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y594,Y600-EPHB1 [plasma membrane]
EPHB1 [plasma membrane]
EPHB1 (18-?) [extracellular region]
EPHB1 (?-984) [cytosol]
EPHB1 (?-?) [plasma membrane]
Inferred To
EPHB1 (?-984) [plasma membrane]
(Bos taurus)
EPHB1 (?-984) [plasma membrane]
(Gallus gallus)
EPHB1 (?-984) [plasma membrane]
(Mus musculus)
EPHB1 (?-984) [plasma membrane]
(Rattus norvegicus)
EPHB1 (?-984) [plasma membrane]
(Sus scrofa)
EPHB1 (?-984) [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004432.1
ZINC - World Drugs
EPHB1_HUMAN
Guide to Pharmacology - Targets
1830
OpenTargets
ENSG00000154928
ENSEMBL
ENST00000493838
,
ENST00000398015
,
ENSP00000419574
,
ENSP00000381097
ZINC - FDA approved
EPHB1_HUMAN
ZINC - Substances
EPHB1_HUMAN
ZINC - Biogenic
EPHB1_HUMAN
ZINC target
P54762
PRO
P54762
GlyGen
P54762
PDB
6UMW
,
7KPM
,
3ZFX
,
2DJS
,
7KPL
,
5MJB
,
2EAO
,
5MJA
ZINC - Investigational
EPHB1_HUMAN
IntEnz
2.7.10.1
HPA
ENSG00000154928-EPHB1
Pharos - Targets
P54762
ZINC - Predictions - Purchasable
EPHB1_HUMAN
HMDB Protein
HMDBP01186
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14451 GRB7
1
GRB7 [cytosol]
(R-HSA-204819)
0.508
4
UniProt:Q13322 GRB10
2
p-Y GRB10 [cytosol]
(R-HSA-9706168)
GRB10 [cytosol]
(R-HSA-110009)
0.499
2
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.499
2
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