Follicle-stimulating hormone (FSH) is a dimeric glycoprotein hormone synthesized and secreted by gonadotropes in the anterior pituitary gland. FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body. The actions of FSH are mediated by the FSH receptor (Minegishi T et al, 1991), found in the ovaries, testes and uterus.Once activated, the receptor mediates its action by coupling to the G protein alpha-s subunit (Timossi C et al, 2002), which activates adenylate cyclase and increases intracellular cAMP levels.
Minegish T [corrected to Minegishi, T, Minegishi, T, Igarashi, M, Nakamura, K, Takakura, Y, Ibuki, Y
Ulloa-Aguirre, A, Conn, PM, Timossi, C, Maldonado, D, Vizcaino, A, Lindau-Shepard, B
© 2023 Reactome
