Hormone ligand-binding receptors

Stable Identifier
R-HSA-375281
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Hormone ligand-binding receptors
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The class A (rhodopsin-like) GPCRs that bind to hormone ligands are annotated here. The hormones follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH) and human chorionic gonadotrophin (hCG) are dimeric glycoproteins, sharing an identical alpha subunit and varying beta subunits. Their actions are mediated by the respective GPCRs, influencing reproductive processes and thyroid hormone release.

Literature References
PubMed ID Title Journal Year
11917095 Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships

Fremont, V, Szkudlinski, MW, Weintraub, BD, Ronin, C

Physiol Rev 2002
11750726 Structural biology of human follitropin and its receptor

Dias, JA, Van Roey, P

Arch Med Res 2001
11861490 GnRH and GnRH receptor genes in the human genome

Neill, JD

Endocrinology 2002
11943741 The lutropin/choriogonadotropin receptor, a 2002 perspective

Segaloff, DL, Ascoli, M, Fanelli, F

Endocr Rev 2002
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Orthologous Events
Hormone ligand-binding receptors (Bos taurus)
Hormone ligand-binding receptors (Caenorhabditis elegans)
Hormone ligand-binding receptors (Canis familiaris)
Hormone ligand-binding receptors (Danio rerio)
Hormone ligand-binding receptors (Drosophila melanogaster)
Hormone ligand-binding receptors (Gallus gallus)
Hormone ligand-binding receptors (Mus musculus)
Hormone ligand-binding receptors (Rattus norvegicus)
Hormone ligand-binding receptors (Sus scrofa)
Hormone ligand-binding receptors (Xenopus tropicalis)
Authored
Jassal, B  (2009-02-23)
Reviewed
D'Eustachio, P  (2009-03-02)
Created
Jassal, B  (2008-08-21)
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