Reactome | SLC7A1 (CAT-1)-mediated uptake of cationic amino acids

SLC7A1 (CAT-1)-mediated uptake of cationic amino acids

Stable Identifier

R-HSA-375776

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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SLC7A1 (CAT-1)-mediated uptake of cationic amino acids

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SLC7A1 mediates the uptake of cationic amino acids across the plasma membranes of non-epithelial cells (Broer 2008; Closs et al. 1997; Furesz et al. 2002; Kamath et al. 1999).

Literature References

PubMed ID	Title	Journal	Year
18195088	Amino acid transport across mammalian intestinal and renal epithelia Broer, S	Physiol Rev	2008
9174363	Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties Cunningham, JM, Habermeier, A, Forstermann, U, Closs, EI, Graf, P	Biochemistry	1997
12202949	Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes Smith, CH, Kamath, SG, Heath-Monnig, E, Furesz, TC	J Membr Biol	2002
10485994	Identification of three cationic amino acid transporters in placental trophoblast: cloning, expression, and characterization of hCAT-1 Smith, CH, Kamath, SG, Way, BA, Furesz, TC	J Membr Biol	1999