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CXCR6 [plasma membrane]
Stable Identifier
R-HSA-373825
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-X-C chemokine receptor type 6, CXCR6_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
Receptor CXCR6 binds CXCL16 ligand (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCR6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00574 CXCR6
Gene Names
CXCR6, BONZO, STRL33, TYMSTR
Chain
chain:1-342
Reference Genes
BioGPS Gene:10663 CXCR6
COSMIC (genes):CXCR6 CXCR6
CTD Gene:10663 CXCR6
dbSNP Gene:10663 CXCR6
ENSEMBL:ENSG00000172215 CXCR6
HGNC:16647 CXCR6
KEGG:hsa:10663 CXCR6
Monarch:10663 CXCR6
NCBI Gene:10663 CXCR6
OMIM:605163 CXCR6
UCSC:O00574 CXCR6
Reference Transcript
RefSeq:XM_011533290.2 CXCR6
RefSeq:XM_005264809.2 CXCR6
RefSeq:NM_006564.1 CXCR6
RefSeq:XM_011533291.2 CXCR6
Other Identifiers
10663
11729977_a_at
16940154
206974_PM_at
206974_at
211469_PM_s_at
211469_s_at
2620774
2620775
2620776
2620777
2620778
2620779
36293_at
8079377
A_14_P117415
A_14_P131797
A_24_P46066
GE59388
GO:0002376
GO:0004930
GO:0004950
GO:0005886
GO:0006935
GO:0006954
GO:0006955
GO:0007186
GO:0007204
GO:0009897
GO:0015026
GO:0016020
GO:0016493
GO:0016494
GO:0019079
GO:0019722
GO:0019957
GO:0048870
GO:0060089
GO:0060326
GO:0070098
HMNXSV003044221
ILMN_1674640
PH_hs_0002841
PH_hs_0031152
TC03000253.hg
g2209287_3p_a_at
g5730105_3p_at
Participates
as an input of
Receptor CXCR6 binds CXCL16 ligand (Homo sapiens)
as a component of
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
Inferred To
npr-32 [plasma membrane]
(Caenorhabditis elegans)
CXCR6 [plasma membrane]
(Bos taurus)
CXCR6 [plasma membrane]
(Canis familiaris)
CXCR6 [plasma membrane]
(Sus scrofa)
Cxcr6 [plasma membrane]
(Mus musculus)
Cxcr6 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011531592.1
,
NP_006555.1
,
XP_011531593.1
,
XP_005264866.1
Guide to Pharmacology - Targets
73
ENSEMBL
ENSP00000304414
,
ENST00000457814
,
ENST00000458629
,
ENSP00000395704
,
ENST00000304552
,
ENST00000438735
,
ENSP00000396218
,
ENSP00000396886
OpenTargets
ENSG00000172215
HPA
ENSG00000172215-CXCR6
PRO
O00574
Pharos - Targets
O00574
GlyGen
O00574
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