Netrin-1 induced DCC clustering

Stable Identifier
R-HSA-373707
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Netrin-1 induced DCC clustering
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Netrin binding to DCC causes DCC clustering via its P3 domain in the cytoplasmic region and mediates attractive signaling.
Literature References
PubMed ID Title Journal Year
15960985 The Netrin family of guidance factors: emphasis on Netrin-1 signalling

Barallobre, MJ, Pascual, M, Del Rio, JA, Soriano, E

Brain Res Brain Res Rev 2005
25123307 The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue

Finci, LI, Krüger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, HDT, Svergun, DI, Zhang, Y, Wang, JH, Meijers, R

Neuron 2014
8861902 Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

Keino-Masu, K, Masu, M, Hinck, L, Leonardo, ED, Chan, SS, Culotti, JG, Tessier-Lavigne, M

Cell 1996
15494734 Activation of FAK and Src are receptor-proximal events required for netrin signaling

Li, W, Lee, J, Vikis, HG, Lee, SH, Liu, G, Aurandt, J, Shen, TL, Fearon, ER, Guan, JL, Han, M, Rao, Y, Hong, K, Guan, KL

Nat Neurosci 2004
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Authored
Garapati, P V  (2008-07-16)
Reviewed
Cooper, HM  (2010-02-16)
Created
Garapati, P V  (2008-07-16)
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