Netrin-1 induced DCC clustering

Stable Identifier
R-HSA-373707
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Netrin-1 induced DCC clustering
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Netrin binding to DCC causes DCC clustering via its P3 domain in the cytoplasmic region and mediates attractive signaling.
Literature References
PubMed ID Title Journal Year
15960985 The Netrin family of guidance factors: emphasis on Netrin-1 signalling

Barallobre, MJ, Pascual, M, Soriano, E, Del Rio, JA

Brain Res Brain Res Rev 2005
15494734 Activation of FAK and Src are receptor-proximal events required for netrin signaling

Vikis, HG, Aurandt, J, Shen, TL, Fearon, ER, Lee, J, Lee, SH, Hong, K, Li, W, Guan, JL, Guan, KL, Rao, Y, Han, M, Liu, G

Nat Neurosci 2004
11239160 Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

Stein, E, Poo, M, Zou, Y, Tessier-Lavigne, M

Science 2001
Participants
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Output
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Orthologous Events
Netrin-1 induced DCC clustering (Caenorhabditis elegans)
Netrin-1 induced DCC clustering (Danio rerio)
Netrin-1 induced DCC clustering (Drosophila melanogaster)
Netrin-1 induced DCC clustering (Xenopus tropicalis)
Authored
Garapati, P V  (2008-07-16)
Reviewed
Cooper, HM  (2010-02-16)
Created
Garapati, P V  (2008-07-16)
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