While noradrenaline is synthesized in the secretory vesicle, its conversion to adrenaline is mediated by a cytosolic enzyme. The process by which noradrenaline is transported across the vesicle membrane has not been worked out, however.
Pacak, K, McNeil, AR, Eisenhofer, G, Christie, DL, Phillips, JK, Lipski, J, Cleary, S, Brouwers, FM
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