Noradrenaline translocates to the cytosol

Stable Identifier
R-HSA-351604
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
secretory granule membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Noradrenaline translocates to the cytosol
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
While noradrenaline is synthesized in the secretory vesicle, its conversion to adrenaline is mediated by a cytosolic enzyme. The process by which noradrenaline is transported across the vesicle membrane has not been worked out, however.
Literature References
PubMed ID Title Journal Year
16047163 Expression of the noradrenaline transporter and phenylethanolamine N-methyltransferase in normal human adrenal gland and phaeochromocytoma

Cleary, S, Brouwers, FM, Eisenhofer, G, Pacak, K, Christie, DL, Lipski, J, McNeil, AR, Phillips, JK

Cell Tissue Res 2005
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
transmembrane transport (0055085)
Cross References
RHEA
Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-05-27)
Cite Us!