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Release of 78 kDa glucose-regulated protein
Stable Identifier
R-HSA-351323
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
,
extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
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Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Release of 78 kDa glucose-regulated protein (Homo sapiens)
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After Platelet activation '78 kDa glucose-regulated protein' from the endoplasmic reticulum lumen is released in to the extracellular platelet releasate.
Literature References
PubMed ID
Title
Journal
Year
6457647
Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa.
Hagen, I
,
Gogstad, GO
,
Solum, NO
,
Korsmo, R
Biochim Biophys Acta
1981
Participants
Input
HSPA5 [endoplasmic reticulum membrane]
(Homo sapiens)
Output
HSPA5 [extracellular region]
(Homo sapiens)
Participates
as an event of
Platelet degranulation (Homo sapiens)
Inferred From
Release of 78 kDa glucose-regulated protein (Mus musculus)
Authored
Farndale, R (2004-09-25)
Pace, NP (2004-09-25)
de Bono, B (2004-09-25)
Reviewed
Humphries, MJ (2008-05-07)
Yamada, KM (2008-05-07)
Hynes, R (2008-05-07)
Created
Garapati, P V (2008-05-22)
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