N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal)

Stable Identifier
R-HSA-351229
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
peroxisomal matrix, cytosol
ReviewStatus
5/5
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N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal)
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The N1-acetylation of spermidine and spermine by spermidine/spermine acetyltransferase (SSAT) is a crucial step in the regulation of the cellular polyamine levels in eukaryotic cells. The kinetics of this enzyme has been already elucidated (Hedge et al. 2007).
Literature References
PubMed ID Title Journal Year
17516632 Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase

Vetting, MW, Yu, M, Hegde, SS, Chandler, J, Blanchard, JS

Biochemistry 2007
15784477 Polyamines: metabolism and implications in human diseases

de Bandt, JP, Cynober, L, Moinard, C

Clin Nutr 2005
Participants
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Output
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Event Information
Go Biological Process
peroxisomal transport (0043574)
Authored
Gopinathrao, G  (2008-05-21)
Reviewed
D'Eustachio, P  (2008-06-12)
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